Damage through excitation and the paradoxical properties of an injured neuron Usually, although not in every case, damage, evoked by various factors, injures cells through excessive excitation [797, 642, 742]. Necrotic neuronal damage often is a fee paid for excitation. Mild or strong excitations are at the core of injury evoked by various insults. Neuroexcitatory […]
Second messengers and cell survival Second messengers, in any cell, evidently, execute general basic functions, but particular functions may appear and disappear in specific cells. Cellular damage and damage-related processes are closely connected with the systems of second messengers, Ca2+ and cyclic AMP, which participate in signal trans-duction within a cell and control a variety […]