Environmental Engineering Reference
In-Depth Information
Compounds and activities: The bioactive compound, muscoride A, isolated
from this species has antibacterial properties (Rao, 2004), and nostopeptin
A and B (cyclic depsipeptides) of this species are elastase and chymotrypin
inhibitors. Other compounds present in this species are microviridins B and
H (cyclic peptides). The extract of this species has also shown antibacterial
and antifungal activities, and the values of inhibition zone diameter (mm)
recorded for the bacterial species, S. epidermidis , S. aureus , S. haemo-
lyticus , P. vulgaris , and S. sonnei , were found to be 22, 24, 16, 18, and
15, respectively. Similarly, the values for the antifungal species, C. krusei ,
C. albicans , A. niger , A. fumigatus , and C. neoformans , were 9, 8, 9, 7, and
10 mm, respectively (Ramamurthy et al., 2012).
Leu
Ahp
H 3 C
CH 3
OH
O
H 2 N
O
N
Phe
H
O
O
NH
O
H 3 C
O
N
O
N
N
H 3 C
H
O
OH
O
H 3 C
O
Ac
Gln
NMeTyr
H 3 C
CH 3
Thr
Val
nostopeptins
Trp
Asp
Ser
Glu
O
O
Ala
Ac
Pro
Has
Thr
Thr
OH
Tyr
Tyr
Arg
Lys
microviridin SD1634
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