Simulation Based Analysis of Nanocarrier Internalization: Exciting Challenges with a New Computational Tool - Intracellular Delivery: Fundamentals and Applications - page 144

Table 3 (continued)
Number of process Process rate Equilibrium Rate determining components Decreasing components Increasing components

Decomposition
R16

0.05 100000 pm_Mot_NV_L pm_Mot_NV_L pm_Mot, pm_NV_L

R21 0.01 100000 pm_Mot_NV_D pm_Mot_NV_D pm_Mot, pm_NV_D

R27 0.01 100000 cyt_ NV_L_D cyt_ NV_L_D cyt_NV_D, cyt_Degr

R28 0.01 100000 cyt_NV_L cyt_ NV_L cyt_NV_D, cyt_Degr

R33 0.01 100000 pm_Mot_NV pm_ Mot_NV pm_NV, pm_Mot

Degradation with transport
R6

0.001 100000 lys_NV_L_D_R lys_NV_L_D_R cyt_Degr

R9 0.001 100000 lys_NV_L_D lys_NV_L_D cyt_Degr

Decomposition with transport
R4

0.1 100000 ee_NV_L_D_R ee_NV_L_D_R pm_R, ee_NV_L_D

R11 0.025 100000 cyt_NV_L_D cyt_NV_L_D mit_D, cyt_NV_L

R12 0.01 100000 cyt_NV_L_D cyt_NV_L_D nuc_D, cyt_NV_L

R26 0.005 100000 pm_Lip_NV_L_D pm_Lip_NV_L_D cyt_ NV_L_D, pm_Lip

R38 0.01 100000 cyt_NV_D cyt_NV_D nuc_D, cyt_NV

R39 0.025 100000 cyt_NV_D cyt_NV_D mit_D, cyt_NV

Transformation (2:2)
R13 0.03 100000 cyt_NV_L_D, cyt_Targ cyt_NV_L_D, cyt_Targ cyt_Targ_D, cyt_NV_L

R40 0.03 100000 cyt_NV_D, cyt_Targ cyt_NV _D, cyt_Targ cyt_Targ_D, cyt_NV

Degradation
R23 0.001 100000 cyt_NV_L_D cyt_NV_L_D cyt_Degr

R29 0.001 100000 cyt_NV_L cyt_NV_L cyt_Degr

R30 0.001 100000 cyt_NV cyt_NV cyt_Degr