Biomedical Engineering Reference
In-Depth Information
z i P l 0 6=l l 0 fb l 0 (R i ) b l 0 (L i )g
b l (R i ) b l (L i )
d l = max(c l ; 0) and c l =
max
i: i2 =1
:
+ P i=1 x 0 i x i ) 1
4. Sample from N( ~ ; ~
), where ~
= ( 1
0
and
X
~ =
~
0 0 +
(z i (t i ))x 0 i
:
i=1
5. Sample from G(a + k; b + P l=1 l ):
6.3.2
Under the PO Model
As seen in Section 6.1, there is a strong connection between the PO model
and the logistic distribution. Also, a logistic distribution can be expressed as
a mixture of scaled normal distributions (Devroye, 1986; Holmes and Held,
2006). Motivated by such a relationship, Wang and Lin (2011) proposed the
following data augmentation:
z i = (t i ) + x 0 i + i with constraint zi i 2 C i ;
i N(0; i ); i = (2 i ) 2 ; i KS;
where C i is the same as that under the Probit model and KS denotes the
Kolmogorov{Smirnov distribution. Similar to that under the Probit model,
the augmented likelihood function is a product of normal densities but with
different variance components i . The following Gibbs sampler (Algorithm
6.1) was proposed by Wang and Lin (2011) based on the augmented likelihood
function:
1. Sample latent variables zi i N((t i ) + x 0 i ; i )1 C i for i = 1; ;n.
), where W 0 = v 0 + P i=1 1
2. Sample 0 from N(E 0 ;W 1
0
and
i
o
n
X
k X
E 0 = W 1
1
i
l b l (t i ) x 0 i
v 0 m 0 +
z i
:
0
i=1
l=1
3. Sample l ' for l = 1; ;k. For each l 1, let W l = P i=1 1
b l (t i ).
i
 
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