Biomedical Engineering Reference
In-Depth Information
100.0
90.0
80.0
70.0
60.0
50.0
40.0
30.0
20.0
15 M
10.0
10 M
0.0
5 M
0.5 cc
1 cc
2 cc
Volume of reagents
FIGURE 19.13
Relationships between recorded temperatures at the thermocouple and the conditions for each experiment. The highest concen-
tration (15 mol/L) gave rise to the highest peak and average temperatures.
intravascular or other undesired spillage or tracking would
dominate an injection. This becomes an engineering challenge
to develop a device similar in some respects to an existing multi-
tined needle currently used for single-agent chemical ablation.
The temperature excursion, as high as it is in these injections,
is relatively brief. Furthermore, with the data obtained thus far,
nothing is known about the temperatures extending outward to
the edge of the ablation zone. Three-dimensional imaging such
18.00
16.00
14.00
12.00
10.00
8.00
6.00
4.00
15 M
2.00
10 M
0.0
5 M
0.5 cc
1 cc
2 cc
Volume of reagents
FIGURE 19.14
Relationships between volumes of the coagulum obtained and the conditions of each experiment. The highest volume of coagu-
lum is not seen with the most concentrated reagents and highest volume. For both the lowest and highest concentrations, the coagulum volume
does not vary greatly with change in injection volume.
