Biology Reference
In-Depth Information
A-G-mismatch DNA
glycosylase
Human
MUTYH
Phos
(Ser524)
70,71
Associated with APEX1, PCNA,
RPA, RAD9-RAD1-HUS1
complex, and MSH6
72-74
"
in S-phase
75
Nuc and
Mito
51,69,75,76
Nuc
80
G-T-mismatch DNA
glycosylase
Human
MBD4
-
Associated with MLH1, SIN3A,
and HDAC1
77-79
-
Acetyl
81
SUMO
82
Activity
83,84
Associated with APEX1, CPB,
p300, DMNT3A, DMNT3B,
RXR, RAR, SCR1, p53, p73
a
,
p63
g
,ER
a
, RAD9, and
XPC
78,81,85-91
Nuc
92
TDG
APEX1
"
No cell cycle
dependence
26
Associated with PIR1
93
AP endonuclease
S. cerevisiae
APN1
-
-
Nuc and
Mito
93,94
Associated with POL30
95
Nuc
34
APN2
-
"
in response to
alkylating agents
96
in G
1
-phase
26
Human
APEX1
Acetyl by
p300
97
Phos
98
Ub (K24, K25,
K27)
99
Nitro
100,101
"
Glycosylase activity of UNG1,
SMUG, NTHL1, OGG1, and
TDG
22,30,45,65,66
Associated with MUTYH,TDG,
XRCC1, HSP70, p53, PCNA,
LIG1, FEN1, and
WRN
74,81,102-107
"
Nuc and
Mito
109-111
"
in response to
ROS
108
Associated with PCNA
112,113
APEX2
-
-
Nuc and
Mito
112-115
Phos
116,117
in S-phase
127
Nuc
103,119,120,131
X-ray repair cross-
complementing
group 1
Human
XRCC1
Associated with OGG1,
NTHL1, NEIL1, NEIL2,
MPG, POL
"
,
LIG3, PARP1,
PARP2, UNG2, PNK, CK2,
TDP1, ATPX, PCNA, and
APEX1
25,36,53,66,67,107,116-130
b
(
Continues
)
