Agriculture Reference
In-Depth Information
Animal species (animal number
per group and duration)
Plant species/trait
Parameters
Main results
Authors' interpretation of results
Reference
Glufosinate
ammonium
tolerant
Wistar rats
(10)
Feed intake, body and organ
weights, macroscopy and
histopathology. Haematology.
Blood biochemistry.
Immunology. Permeability of
the intestinal barrier.
Locomotor behaviour.
No difference in any parameters.
No impact of GM maize on
reproductive function of rats
and on progeny
development.
Tyshko
et al
., 2011
Total of 630 adults and 2837
pups. Five groups fed with
GM, control near-isogenic or
three other conventional maize
lines.
T25 event
25 days
F0 and 2 generations
Potato
Glufosinate
ammonium
tolerant
Sprague-Dawley rats
(25 males and 25 females)
10 weeks
Presence of DNA. Feed
consumption. Developmental
and reproductive performance.
No difference in any parameters.
Safe, no multi-generational
effects.
Rhee
et al
., 2005
5 generations
(F0-F4)
Soybean
Glyphosate
tolerant (
CP4-
EPSPS
gene;
event GTS
40-3-2)
8-87 days (from approximately 1
week to approximately 12
weeks; with pregnant mice
and male mice)
Testicular development in mouse
model.
No differences in fetal, post-natal,
pubertal or adult testicular
development.
Safe, no multi-generational
effects.
Brake and Evenson,
2004
4 generations
Glyphosate
tolerant
(
CP4-EPSPS
gene; event
GTS 40-3-2)
Wistar rats
(10 rats)
Weight gain, ration intake, protein
intake and effi cacy ratio.
Some differences between
experimental and control.
Daleprane
et al
.,
2009b
Fed throughout life (duration not
precise) in both generations
(F0 and F1)
