Agriculture Reference
In-Depth Information
Table 8.2.
Continued
Animal species (animal number
per group and duration)
Plant species/trait
Parameters
Main results
Authors' interpretation of results
Reference
Triticale
Glufosinate
ammonium
tolerant
C57Bl/6J mice
(41-60 according to treatment
and generation)
91-day-old mated/killed (at each
generation)
The next generation, up to F5,
over all periods of life
(including gestation and
lactation), fed only with control
or treatment pellets
5 generations
Body weight and growth.
Presence of transgenic DNA.
Pathological manifestations.
No presence of transgenic DNA.
No weight differences. No
pathological manifestations.
Safe, no multi-generational
effects.
Baranowski
et al
.,
2006
Glufosinate
ammonium
tolerant
C57BL/6J mice
(20)
Immune system.
In F5 enlarged inguinal and
axillary lymph nodes detected.
Decrease in T cells in spleen
and lymph nodes and
decrease in B cells in lymph
nodes and blood.
Changes not caused by an
allergy or a malignant
process but further studies
should be undertaken.
Krzyowska
et al
.,
2010
120 days then mated/killed (at
each generation)
(approximately 17)
5 generations
Rice
The gene
encoding lysine-
rich protein (LR)
from winged
bean inserted
into the glutelin
(Gt1)-encoding
Sprague-Dawley rats
(20 females and 10 males)
(20 weanlings/female/group and
10 weanlings/male/group as
F1 generation. F2 generation
the same procedure. F3
Body weight, food consumption,
reproductive data, organ
weight, ratio and pathology,
haematology, serum chemistry,
serum sex hormone levels.
Gross and anatomic pathology.
No adverse behaviour or clinical
effects on F0, F1, F2, F3
generation animals. Mean
corpuscular volume values 2%
higher in F3 female rats in the
GM-rice diet compared with
control diet: no indication of
GM rice as safe as near-
isogenic non-GM rice.
Zhou
et al
., 2012
