Long-term and Multi-generational Animal Feeding Studies - Animal Nutrition with Transgenic Plants - page 122

Table 8.2. Continued

Animal species (animal number
per group and duration) Plant species/trait Parameters Main results Authors' interpretation of results Reference

Bt-MON810
( cry1Ab gene)

Pigs (cross-bred Large White 
Landrace)
(12)

Haematological and immune
functions to detect possible
infl ammatory and allergenic
responses at various times.
Attempts to detect Cry1Ab
protein in blood and faeces at
various times.

Cytokine production similar
between treatments. Some
differences in monocyte,
granulocyte or lymphocyte
subpopulations counts at some
times, but no signifi cant
patterns of changes.

No indication for infl ammation
or allergy due to GM maize
feeding.

Buzoianu et al .,
2012b

Fed for ~143 days (20 weeks)
throughout gestation and
lactation
F0 + 1 generation (offspring at
birth)

Bt-MON810
( cry1Ab gene)

Pigs (cross-bred Large White 
Landrace)
(10)

Pig growth performance body
weight and feed
disappearance recorded at the
time of each dietary change
(weaning (day 0), on day 30,
70, and 100) and at harvest
(day 115). At harvest, organ
weight, histological
observations, cold carcass
weight. Serum biochemistry.

No pathology observed in the
organs. Offspring of sows fed
Bt maize had improved growth
throughout their productive life
compared to offspring of sows
fed non-GM maize, regardless
of the maize line fed between
weaning and harvest. Some
minor differences in average
daily gain, carcass and spleen
weights, dressing percentage,
duodenal crypt depths for
offspring from GM fed or in
average daily feed intake for
offspring from sows fed GM
and for GM-fed pigs or in liver
weight for pigs in the Bt/Bt.

Trans-generational
consumption of GM maize
diets not detrimental to pig
growth and health.

Buzoianu et al .,
2012c

Maize dietary inclusion rate
identical between treatments
(isogenic parent line maize
from service to weaning and
GM maize from service to
weaning (Bt)) and ranged from
86.6% during gestation to
74.4% during lactation)

Offspring fed for 115 days in 4
dietary treatments
(20 weeks)