Environmental Engineering Reference
In-Depth Information
Table 7
The
in vitro
toxicity of ENPs in different cell lines
Nanoparticle
Concentration
Cell line
Results
References
Fullerene
0.24-2,400ppb Human dermal ibroblast and
human liver carcinoma
Oxidative damage and cell death
Colvin(
2002
), Sayes
etal.(
2004
)
Carbonblack
5, 10, 20, 50 and
100 ʼg/mL
Mouse embryo ibroblast
CytotoxicitywasobservedinorderZnO>SWNTs>SiO
2
Yangetal.(
2009
)
SWNTs
SiO
2
ZnO
Superparamagnetic iron
oxide
>14.5,29and
58mg/mL
Mouse ibroblasts
Gasvesicleformation
Mahmoudi et al.
(
2010
)
SWNTs
800g/mL
A549cellline(human)
Loss of cell membrane integrity, inlammation, low toxicity Davorenetal.(
2007
)
CuO, TiO
2
, ZnO, CuZnFe
2
O
4
,
Fe
3
O
4
, Fe
2
O
3
and MWNTs
0-80 ʼg/mL
Human lung epithelial
DNA damage and oxidative lesion
Karlssonetal.(
2008
)
CuO
-
Human lung epithelial
Reduced cellular viability, glutathione production
Ahamedetal.(
2010
)
PVP coated Ag
0-7.5 ʼg/ml
Human monocytic
Reactive oxygen species generation
Foldbjergetal.(
2009
)
Ag
0-250 ʼg/mL Rat liver
ToxicityinorderAg>MoO
3
>Fe
2
O
3
:Al: TiO
2
, abnormal
andirregularcellshapeandcellshrinkage
Hussainetal.(
2005
)
MoO
3
Al
Fe
2
O
3
TiO
2
TiO
2
2 ʼg/mL
Lung tumor
Alteredcellmorphologyandinternalizationandcelldeath Magrezetal.(
2009
)
CeO
2
-
Human bronchial epithelial cell
and macrophage
Antioxidant,cytoprotective(CeO
2
)ROSproduction(ZnO) Xiaetal.(
2008
)
ZnO
Magnetic nanoparticle
150 ʼM and 1.5,
15 mM
Rat Pheochromocytoma
Decreased cell viability and neuritis extension
Pisanicetal.(
2007
)
TiO
2
-
Isolatedporcineskin
No penetration
Wuetal.(
2009
)
C
60
and 14 C labeled
ammonium salt derived C
60
2 ʼM
Humankeratinocytes
Accumulation in cell and growth inhibition
Bullard-Dillard et al.
(
1996
)
Ag and Au
17.4and19mg/L Rainbow trout hepatocytes
Cytotoxicity and membrane disruption
Farkasetal.(
2010
)
Citrate and PVP coated silver 0.1-10mg/L
Rainbow trout primary gill cell
Cellular absorption and increased glutathione production Farkasetal.(
2011
)
Search WWH ::
Custom Search