New Insights into the Role of BubR1 in Mitosis and Beyond - International Review of Cell and Molecular Biology - page 228

Table 6.1 Posttranslational modifications of BubR1 — cont'd
Phosphorylation

Mutant phenotype PO 4

in
taxol Notes

PO 4 in
nocodazole

S/T!A S/T!D/E

Residue Presumed enzyme References

Tension-
sensitive,
KARD
domain

Elowe et al. (2007) ,
Suijkerbuijk et al. (2012b) ,
and Matsumura et al. (2007)

Attachment
defect S676 Plk1 Yes Yes

T680 Plk1 Attachment

defect

Rescues Plk1
depletion
phenotype

Attachment-
sensitive,
KARD
domain

Suijkerbuijk et al. (2012b)

S720 Attachment

defect

Elowe et al. (2010)

T792 Plk1 Attachment

defect

Rescues Plk1
depletion
phenotype

Matsumura et al. (2007)

T1008 Plk1 Attachment

defect

Rescues Plk1
depletion
phenotype

Matsumura et al. (2007)

S1043 Mps1 ( Huang et al.,
2008 ); Cdk1 ( Elowe
et al., 2010 )

Huang et al. (2008)
and Elowe et al. (2010)