Biomedical Engineering Reference
In-Depth Information
Macrocycle BRD-0476
Suppressor of
-cell
apoptosis; EC
50
=
0.78
M
Cytokine-induced
-cell
death
26
Pyridopyrimidinone
CMLDBU6128
Orthopoxvirus inhibitor;
IC
50
=
5.3
Mat12h
postinfection
Fluorescent detection of
viral fusion proteins
27
Macrocycle ML238
Anti-
Plasmodium
falciparum
(antimalarial) activity;
GI
50
=
0.54 nM
Blood-stage malaria
assay with a DAPI
reporter
28
1,4-Thiazepine analog
Cytotoxic activity
inhibition rate of
66.82% at 1 mg/mL
Cytotoxicity against
carcinoma HCT-116
cells
29
