Biomedical Engineering Reference
In-Depth Information
TABLE 18.1
( Continued )
Structure
Name
Activity
Assay
Ref.
Polycyclic ketal,
indoline alkaloid, and
guanidine chemotypes
Plasmodium falciparum
inhibitor (antimalaria);
IC 50 = 0.02 M for a
guanidine analog
SYBR green dye DNA
staining assay
23
Fused-bicyclic lactam
analog
Glucose transport
inhibitor; Depletion of
ATP, I C 50 = 1 M
Cell-based assay
determining ATP level
using antimycin
A-sensitized A549 or
CHO cells
24
Naphthyridinone analog
Endothelial cell
activator; activation of
inflammatory pathways
at 10 M
Cellular production of
the chemokine MIP1
25
 
Search WWH ::




Custom Search