INTRODUCTION TO PROCESSING OF BIOMATERIALS - Advanced Biomaterials: Fundamentals, Processing, and Applications - page 260

TABLE 8.4. Different Types of Surface Topography Modifi cations on Biomaterials

Surface
topography Fabrication methods used Material used Dimensions References

General
roughness

Metal - acid etching, nitriding,
plasma - etching, electro - polishing,
ion beam etching

— — [8, 83]

Polymer - sand blasting, polymer
casting, scratching, plasma
treatment

[8, 84]

Grooves Photolithography and reactive ion

etching

PDMS cast of silicon
original

Square grooves
2, 5, 10 μ m width
0.5 μ m depth

—

Photolithography and anisotropic
etching

Ti - coated silicon Square and V - shaped grooves, 7

and 39 μm repeat spacing with 3
or 10 μ m depth

Photolithography and anisotropic
etching

Poly - lysine - coated
quartz

Square grooves
1 μ m width
1 μ m depth

Electron - beam lithography and wet
etching

PDMS cast of silicon
original

Square grooves
2, 5, 10 μ m width

0.5 μ m depth

UV and glow discharge treatment Serum - coated glass 2 μ m width

2 μ m depth

Cutting with diamond or tungsten Poly - D - lysine coated

chrome plated quartz

0.13 - 4.01 μ m width

0.1 - 1.17 μ m depth

Laser holographic technique
used to defi ne masks for X-ray
lithography and reactive ion
etching

Quartz and poly - L -
lysine coated quartz

130 nm width
100 - 400 nm depth