Biomedical Engineering Reference
In-Depth Information
Figure 13.7
PAEK cages were
compared with sterilized allografts in
a Spanish goat study.
Image courtesy of
Bill Christianson, DePuy Spine.
Figure 13.8
Fusion was observed
radiographically in the Spanish goats
after 2-year follow-up. Image courtesy of
Bill Christianson, DePuy Spine.
in a 360
fusion have been reported
[33,34]
,with
superior clinical outcomes as compared with
posterolateral instrumented fusion.
In the mid 1990s, BASF decided to no longer
produce PEKEKK and withdrew the UltraPek resin
from the market. Although AcroMed stockpiled
sufficient UltraPek to support their products, their
cage products were transitioned to PEEK, produced
by Invibio, to provide a long-term biomaterial supply
[27]
. Stockpiled UltraPek continued to be used in
Brantigan cages distributed in Japan until February
2007 when DePuy received Japanese approval for
a CFR-PEEK OPTIMA cage
[27,35]
.
there were no major device-related complications in
the study, 23 major nondevice-related complications
occurred (10.4%), including six deaths. These find-
ings underscored the clinical difficulties associated
with the PLIF procedure for spinal fusion.
The clinical limitations associated with PLIF
were addressed with evolution in surgical technique
to explore anterior lumbar interbody fusion (ALIF)
with the Brantigan cage, as well as the more
extensive “circumferential” or 360
fusion,
involving an ALIF procedure and posterior instru-
mentation with pedicle screws. Two- and 5- to
9-year follow-up data for the ALIF Brantigan cage
