Biomedical Engineering Reference
In-Depth Information
Santos (220) (2005)
20% ALA, 3 hr/
split-face: IPL
alone vs. IPL+ALA
Face/not mentioned
2 (2 wk apart)
13
IPL cutoff fi lter,
560 nm,
26-34 J/cm
2
Improvement
signifi cantly
higher in
ALA-PDT side:
10/13 had good or
excellent results
vs. IPL only: 3/13
had good results
at 8 wk
8 wk
Rojanamatin (219)
(2006)
20% ALA, 30 min
under occlusion/
split-face IPL +
placebo vs. IPL +
ALA
Face/soap and water
3 (3-4 wk apart)
14
IPL cutoff fi lter
560-590 nm,
25-30 J/cm
2
IPL + ALA: 87.7%
vs. IPL + placebo:
66.8% reduction
of infl ammatory
lesions
12 wk
Alexiades-Armenakas
(224) (2006)
20% ALA, 45 min/
ALA topical +
LPDL or blue light
vs. LPDL only vs.
conventional
therapy.
Superfi cial chemical
peels in 6 patients
(2 control and 4
ALA-LPDL)
Face/Cetaphil
cleanser
1-6 (monthly)
19: 1 ALA + blue,
14 ALA+LPDL,
4 control
(2 LPDL only and
2 conventional
therapy)
LPDL (595 nm,
7-7.5 J/cm
2
,
6-10 msec,
10 mm spot size,
blue light
ALA+LPDL: 77%
clearance rate per
treatment vs.
LPDL only: 32%
vs. conventional
therapy: 20%
13 mo
Wiegell (229) (2006)
16.8% MAL, 3 hr
under occlusion/
treatment ×
control group
Face/curettage
2 (2 wk apart)
31 (19 treatment vs.
12 control)
Noncoherent red
(630 nm),
37 J/cm
2
MAL-PDT: 68%
reduction of
infl ammatory
lesions vs. 0% in
control
12 wk
Wiegell (228) (2006)
Split-face 20% ALA
vs. 16.8% MAL,
3 hr under
occlusion
Face/not mentioned
1
15
Noncoherent red
(630 nm),
37 J/cm
2
,
34 mW/cm
2
59% reduction of
infl ammatory
lesions for both
MAL and ALA
12 wk
Hörfelt (227) (2006)
16.8% MAL, 3 hr
under occlusion/
split-face
treatment ×
control group
Face/nodular
lesions were
prepared using a
cannula (1-2 mm)
2 (2 wk apart)
30
Noncoherent red
(630 nm),
37 J/cm
2
MAL-PDT-side:
54% clearance of
infl ammatory vs.
control-side: 20%
10 wk after last
treatment
Gold (218) (2007)
20% ALA,
15-30 min
Face/cleanser
4 (2 wk apart)
15
IPL (420-950 nm),
5-7 J/cm
2
,
30-50 msec
54.5% reduction of
infl ammatory
lesions
11 wk
(
Continued
)
