The Art of Bioconjugation: Functionalization of VNPs - Viral Nanoparticles: Tools for Materials Science and Biomedicine - page 112

Ad Lys (E) EDC/NHS Using Ad as a

photosensitizer
for
photodynamic
therapy

Allen et al . Phthalocyanines

(1999)

Ad Lys (E) Nanogold

and anti-CEA
fragment
(MFE)

NHS ester
Non-covalent
attachment of
sCAR-MFE

Hyperthermia
treatment for
tumor therapy

Everts et al .

(2006)

Ad Hexa-His tag (E;

GE)

Nanogold
and anti-CEA
fragment
(MFE)

Non-covalent
hexa-His-Ni-NTA
interactions and
non-covalent
attachment of
sCAR-MFE

Hyperthermia
treatment for
tumor therapy

Saini et al .

(2008)

CPV Lys (E) Fluorescent

dyes

NHS ester Development

of CPV for
biomedical
targeting
applications

Singh et al .

(2006)

PVX Lys (E) Fluorescent

dyes and PEG

NHS ester; NHS-
alkyne followed
by click chemistry

Development
of PVX for
biomedical
applications

Steinmetz et

al . (2009c)

TMV Lys (E; GE) Biotin and

fluorescent
dyes

NHS ester Proof-of-concept Demir and

Stockwell
(2002)

TMV Tyr (E)

Glu (I)

Biotin,
PEG, small
chemicals, and
fluorescent
dyes

Diazonium
coupling, oxime
condensation,
EDC/NHS

Proof-of-concept Schlick et al .

(2005)

TMV Tyr (E) PEG and RGD Diazonium

(aniline-alkyne)
followed by click
chemistry

Development
of TMV for
biomedical
applications

Bruckman
et al . (2008)

TMV Cys (E; GE) Fluorescent

dyes

Maleimide Immobilization

and fabrication
of microarrays

Yi .

(2005, 2007)

et al

TMV Cys (I; GE) Fluorescent

dyes,
porphyrins or
pyrene

Maleimide Light-harvesting

systems

Ma .

(2008), Endo
et al

et al

. (2006,
2007), Miller
et al

. (2007)

M13 N-term of pVIII NIR

fluorophores

NHS ester VNP-based

probes for
biomedical
imaging

Hilderbrand
et al . (2005,

2008)

M13 Amines (Lys and

amino-terminus;
not specified)

Iron oxide
nanoparticles

Epichlorhydrin Magnetophage

for MRI

Segers et al .

(2007)