Biomedical Engineering Reference
In-Depth Information
D. melanogaster
.
conventional.
kinesin.(full.
length.Kin-1)
Glide;.docked.kinesin.
motors;.capped.
microlithographic.
channels.(rather.than.
open);.rhodamine-
labeled.MTs
Inverted.motility.assay.with.
enclosed.luidic.channels;.
kinesin-MT
Transport.of.functionalized.
MTs.over.long.distances.for.
integration.into.nanodevices;.
prevention.of.MT.diffusion.
away.from.device
Proven.functional.for.keeping.
MTs.proximate.to.surface;.
enclosed.regions.shown.
successful.in.devices.for.
concentrating.analytes
Huang.et.al..
(2005);
Lin.et.al..(2008)
D. melanogaster
.
conventional.
kinesin.(full.
length.Kin-1)
Glide;.docked.kinesin.
motors;.
thermoresponsive.
polymer.surface.
controls.MT-kinesin.
interaction
Inverted.motility.assay.with.
external.mechanism;.
poly(N-
isopropylacrylamide).
grafted.surface.polymers.
expand.at.low.temperatures.
and.prevent.MT-kinesin.
interaction;.contract.at.
warmer.temperatures.and.
permit.motility
Selective.motility.of.
molecular.shuttles;.
integration.with.inorganic.
devices.for.transport,.
sorting,.etc.
Experimentally.viable.for.
controlling.molecular.shuttle.
dynamics/association.with.
motors;.candidate.for.shuttle.
control.in.more.complex.
devices;.particular.
temperature.dependence.poses.
a.threat.to.incorporation.
within.practical.systems
Ionov.et.al..
(2006)
NKHK560.cys:.
H. sapien
.
kinesin.stalk.
(residues.
430-560).with.
head/neck.
domains.of.
N. crassa
.
kinesin.(amino.
acids.1-433);.
cysteine.
C-terminal.end.
(reactive)
Glide;.docked.kinesin.
motors;.active.
transport.guidance.of.
biotinylated.MT.
shuttles.over.
functionalized.motors.
by.way.of.
microlithographic.
design.construction.
toward.a.sensor
Fluorescently.labeled.
analytes.on.MT.shuttles.
directed.over.docked.
kinesin.motors;.8.large.
channels/sorting.regions.of.
a.microlithographic.
concentration.device.taper.
down.to.a.collection/
detainment.region;.guided.
MTs.are.trapped.and.the.
aggregation.process.
(spanning.one.hour).is.
observed.luorescently;.
detainment.area.capped.
with.parylene.cover
Guided.mass-transport.of.
analyte.carrying.molecular.
shuttles.to.particular.
locations.on.NEMS,.MEMS,.
lab-on-a-chip.devices;.
prevention.of.MT.diffusion.
away.from.device.surfaces;.
self-sorting
Proven.experimentally.as.a.
successful.device.for.
concentrating.analytes.to.a.
particular.location.for.sensing;.
incorporation.into.functional.
application.has.not.yet.
occurred
Lin.et.al..(2008)
(continued)
