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Fig. 7. The complete network of spliceosome assembly modeled as transition bounded Petri net. The different stages are
labeled with capital letters: E = E-complex, A = A-complex, B = B-complex, TRI = tri-snRNP complex, C = C-complex
and R = recycling pathways. Places are colored according to different functions: orange = proteins with RS domains; blue =
RNA; magenta = DExD/H box proteins functioning as ATP dependent “RNA unwindases”; gray or hatched = logical places,
indicating equal places occurring more than once in the figure, but not in the underlying graph structure of the PN. Transitions
represented by two squares introduce hierarchical nodes, which connect to further reactions at a lower network level (see Fig. 9).
(Colours are visible in the online version of the article at www.iospress.nl . )
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