Biology Reference
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Dynamics of Gene Expression
1.11
1.1
1.09
1.08
P190
P210
1.07
1.06
1.05
1.04
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Chromosomes
Fig. 5.2.
Average gene expression changes on each chromosome.
5.1.3.3.
Absolute difference between P190
and P210 (Fig. 5.3)
(
∑
|
e
p190
(
i
,
j
) −
e
p210
(
i
,
j
)|
)
/
n
(
j
).
Absolute difference (
j
)
=
Here,
e
(
i
,
j
) are expression fold changes and
n
(
j
) are the numbers of genes
in every chromosome group;
j
1, 2, … ,
n
(
j
).
We find that the No. 4 chromosome has the highest differential expres-
sion across the two datasets.
=
1, 2, … , 20;
i
=
5.1.3.4.
Prefiltering process (gene selection)
There were only a small number of genes in the P190 and P210 datasets
that were differentially expressed across the two datasets. Genes with
lower standard deviations across the two samples were removed. A total
of 8832 genes in the P190/P210 data set were selected, the deviation
ranging from 2 to 6.68.
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