Biomedical Engineering Reference
In-Depth Information
Figure 11.14
Schematic representation of core-shell nanoparticles.
typically composed of type II-VI, IV-VI, and III-V semiconductors, with
coni gurations such as CdS/ZnS, CdSe/ZnS, CdSe/CdS, and InAs/CdSe
(typical notation is: core/shell). Organically passivated quantum dots have
low l uorescence quantum yield due to surface related trap states. CSNPs
address this problem because the shell increases quantum yield by pas-
sivating the surface trap states. In addition, the shell provides protection
against environmental changes, photo-oxidative degradation, and pro-
vides another route for modularity. Precise control of the size, shape, and
composition of the core and shell enable the emission wavelength to be
tuned over a wider range of wavelengths than with either individual semi-
conductor. h ese materials have found applications in biological systems
and optics.
Taking into account the recognition element for sensors linked to MIPs,
a proliferation of interest has been witnessed by those who are interested in
this subject [33]. Indeed, MIP nanoparticles are theme, which recently has
come to light in the literature. Keeping this in mind, Gültekin
et al.
have
proposed a novel thiol ligand-capping method with polymerizable methac-
ryloylamidocysteine (MAC) attached to gold nanoparticles, reminiscent of
a self-assembled monolayer. Furthermore, a surface shell by synthetic host
polymers based on molecular imprinting method for recognition has been
reconstructed. In this method, methacryloyl iminodiacetic acid-chrome
{MAIDA-Cr(III)} has been used as a new metal-chelating monomer via
metal coordination-chelation interactions and dipicolinic acid (DPA)
which is the main participant of Bacillus cereus spores has been used as a
template. Nanoshell sensors with templates produce a cavity that is selec-
tive for DPA. h e DPA can simultaneously chelate to Cr(III)-metal ion and
i t into the shape-selective cavity. h us, the interaction between Cr(III) ion
and free coordination spheres has an ef ect on the binding ability of the
