Biomedical Engineering Reference
In-Depth Information
50% KOH aq, Toluene-CHCl
3
(7:3), -20
C
94
94 (
S
)
11
+
Q
3Br
-
+
H
N
=
Q
+
+
O
Q
N
+
Q
7b
(3 mol%)
Me
4-MeO-C
6
H
4
CsOH H
2
O, Toluene-CH
2
Cl
2
(7:3), -70
C
87
93 (
R
)
12
+
N
O
Me
t
-Bu
2I
-
4-MeO-C
6
H
4
4-MeO-C
6
H
4
O
+
N
Me
4-MeO-C
6
H
4
8a
(10 mol%)
MeO
H
OMe
H
1 M KOH aq, CH
2
Cl
2
,0
C
55
90 (
R
)
13
+
N
N
H
N
H
O
O
Cl
-
Me
Me
9
(30 mol%)
Ar
50% KOH aq, Toluene, 0
C
88
96 (
R
)
14
Ar
Br
-
+
N
Ar
Ar
(
S
,
S
)-
10
(1 mol%) (Ar = 3,5-Ph
2
-C
6
H
3
)
(
continued
)
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