ASYMMETRIC PHASE-TRANSFER CATALYSIS - Modern Tools for the Synthesis of Complex Bioactive Molecules - page 216

TABLE 7.1 (Continued )

ee (%)
(Configuration) Catalyst (mol%) Conditions Yield (%) Reference

Ar

50% KOH aq, Toluene, 0 C

Ar

87 97 ( R ) 15

Ar

Ar

Br -

+

N

Ar

Ar

Ar

Ar

( S , S )- 11a (1 mol%) (Ar = 3,5-Ph 2 -C 6 H 3 )

Si

50% KOH aq, Toluene, 0 C

Si

96 99 ( R ) 16

Si

Si

Br -

+

N

Si

Si

Si Si

( S , S )- 11b (1 mol%) ( Si = SiMe 2 Oct)

R 2 R 1

50% KOH aq, Toluene, 0 C

81 95 ( R ) 17

Br -
+

N

R 2 R 1

( S )- 12 (1 mol%) (R 1 = 3,5-Ph 2 -C 6 H 3 ,R 2 = Ph)