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CG
250
250
CW
Captopril
Captopril
200
200
Tamoxifen
Tamoxifen
150
150
100
100
50
50
0 060
90
120
0
30
60
90
120
TDG
∗
TDW
250
250
Captopril
Ω
∗
Captopril
Ω
Tamoxifen
200
200
Tamoxifen
Ω
Ω
150
150
100
100
50
50
0 060
90
120
0
30
60
90
120
TSW
TSG
250
250
Captopril
Captopril
200
200
Tamoxifen
Tamoxifen
150
150
100
100
50
50
0 060
90
120
0
30
60
90
120
Time after glucose load (min)
Time after glucose load (min)
Fig. 8.3
Changes in blood glucose concentrations after intravenous injection of a bolus glucose
solution (note that the glucose-supplemented groups are depicted in the three right panels;
CW
control with water intake alone,
CW + Cap
CW plus captopril treatment,
CW + Tam
CW plus
tamoxifen treatment,
CG
control with high sugar intake,
CG + Cap
CG plus captopril treatment,
CG + Tam
CG plus tamoxifen treatment,
TDW
perinatal taurine depletion with water intake alone,
TDW + Cap
TDW plus captopril treatment,
TDW + Tam
TDW plus tamoxifen treatment,
TDG
peri-
natal taurine depletion with high sugar intake,
TDG + Cap
TDG plus captopril treatment,
TDG + Tam
TDG plus tamoxifen treatment,
TSW
perinatal taurine supplementation with water
intake alone,
TSW + Cap
, TSW plus captopril treatment,
TSW + Tam
TSW plus tamoxifen treat-
ment,
TSG
perinatal taurine supplementation with high sugar intake,
TSG + Cap
TSG plus capto-
pril treatment,
TSG + Tam
TSG plus tamoxifen treatment; *
p
< 0.05 compared to baseline of same
group;
Ω
p
< 0.05 compared to all other groups)
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