Chemistry Reference
In-Depth Information
Tab l e 5 . 7
Me
Me
Me
Me
O
Alkene
*
O
H
O
CH
2
Cl
2,
-20 °C, 12 h
*
S
Me
S
Co
Co(CO)
3
Me
OC
CO
53a
54
-
56
Alkene
Product
Yield (%)
Dr
54
77
11.5:1
55
82
24:1
56
91
13.3:1
Me
Me
Me
Me
Me
2
CuLi, Me
3
SiCl,
Et
2
O, -10 °C
O
O
H
H
O
O
80%
S
S
H
H
Me
Me
Me
H
55
(Major diastereomer)
SmI
2,
THF-MeOH, 0 °C;
93% (95% recovery of
9a
)
O
O
H
(-)-
57
H
Me
Me
MeAlCl
2,
maleic anhydride,
CH
2
Cl
2,
55 °C, 2 h;
93%
H
H
Scheme 5.40
