Chemistry Reference
In-Depth Information
Me
Me
Me
Me
H
O
O
OR*
H
O
H
OC
O
S
Co
Co(CO)
3
Me
H
CO
Me
S
H
Scheme 5.41
1)
Me
Cu
O
O
OTBDMS
H
BF
3
·Et
2
O (58%)
O
Ph
H
2) SmI
2
, THF-MeOH (89%)
H
H
H
H
H
Ent
-
47
58
OTBDMS
Me
MeAlCl
2,
maleic anhydride
(66%)
OBu-
n
OH
O
O
OTBDMS
H
OH
CO
2
Bu-
n
LiClO
4
cat; H
3
O
+
(92%)
60
59
O
OTBDMS
OTBDMS
Me
Me
Me
(+)-Brefeldin A
Scheme 5.42
