Steven a. goldman is a stem cell researcher at the University of Rochester. He was previously at Cornell in the Division of Cell and Gene Therapy as the chief of the division. He also held the Glenn-Zutes Chair in Biology of the Aging Brain and was a professor of neurology, neurosurgery, and pediatrics. Goldman graduated summa cum laude with a bachelor’s degree in biology and psychology from the University of Pennsylvania in 1978. In 1983 he completed a medical degree at Cornell University Medical College. However, instead of entering medical practice, he undertook studies for a doctoral degree. He completed his second doctorate in cellular neurobiology at Rockefeller University in 1984.
After completing his formal education, Goldman began the practice of medicine with a residency at the Cornell Medical Center in New York Hospital and Memorial Sloan Kettering Cancer Center in Medicine from 1984 to 1985. He then did a second residency in neurology from 1985 to 1988 and was chief resident in neurology from 1987 to 1988. Earning degrees has allowed Goldman to become certified as a physician. He is certified as a diplo-mate by the National Board of Medical Examiners (1985), with medical licensure by the State of New York (1985), and as a neurologist by the Board of Certification in Neurology, American Academy of Neurology and Psychiatry (1989). Goldman has many NIH grants and has been awarded a number of honors during his productive career.
CAREER AND HONORS
Goldman’s career has been a series of upwardly mobile places of service in neurology. From 1988 to 1992, he was an assistant professor of neurology and an assistant attending neurologist at the New York Hospital-Cornell University Medical Center. From 1992 until 1997, he served as associate professor of neurology and neuroscience at the New York Hospital-Cornell University Medical Center. In 1997 he was granted tenure as associate professor of neurology and neuroscience at the New York Hospital-Cornell University Medical Center. Goldman has a unique combination of both clinical and scientific skills that has kept him at the front of biomedical research in the stem cell field for many years.
From 1997 until 2001, Goldman served as professor of neurology and neuroscience at Cornell University Medical College. In addition, he was senior attending neurologist at New York Presbyterian Hospital. From 2001 until 2003, he was Nathan Cummings Professor of Neurology and Neuroscience at Cornell University Medical College. From 2003 until this writing, he has been adjunct professor of neurology at the Weill Medical College of Cornell University.
Goldman has been the recipient of many awards and fellowships. He was a Benjamin Franklin National Scholar, University of Pennsylvania, 1974-78; a Senatorial Scholar, State of Pennsylvania, 1974-78, and a Mayor’s Scholar, City of Philadelphia, 1974-78. He was elected into Phi Beta Kappa at the University of Pennsylvania (1977) and was a Medical Scientist Training Program trainee, U.S. Public Health Service (1978-84), a Grass Foundation Fellowship winner (1978), and a Cornell Scholar in Biomedical Science (198891). He was given a clinical investigator development award from the National Institutes of Health (NIH)/National Institute of Neurological Disorders and Stroke (NINDS) for two years (198893), a FIRST Award from the NIH/NINDS for five years (1992-97), an Irma T. Hirschl Career Scientist Award for four years (1993-97), and a Jacob Javits Neuroscience Investigator Award from the National Institute of Neurological Disorders for seven years (2002-09).
PROFESSIONAL SERVICE
There are a number of medical and scientific societies to which Goldman belongs. These include the American Society for Clinical Investigation (elected 2001), American Neurological Association (elected 1995), American Academy of Neurology, American Society for Cell Biology, American Society for Gene Therapy, Association for Nervous and Mental Diseases, and American Association for the Advancement of Science Society for Neuroscience.
Government service rendered by Goldman is extensive. It includes service on the NIH/NINDS Broad agency/RFP 96-07 review panel, NINDS Neuro-B2 review committee (1997), NINDS/Small Business Innovative Research review committee (1998), NINDS Neural Stem Cell Advisory Committee (1999), NINDS Special Emphasis Panel ZNS1-L01 (2000), U.S. Food and Drug Administration Stem Cell/Biological Response Modifiers Advisory Committee (2000), National Heart, Lung, and Blood Institute Scientific Review Group (SRG; Stem Cell Plasticity) (2001), NINDS Molecular, Cellular, and Developmental Neurosciences (MDCN) 7 (2001), NINDS MDCN6 (2002), National Institute of Mental Health SRG (2002), NINDS MDCN6 (2003), NINDS SRG (2003), National Institute on Aging SRG (2004).
Professional society and foundation service by Goldman includes acting as a neurobiology of disease workshop coordinator for the Society for Neuroscience (2002), participating in the Neural Disorders Committee of the American Society for Gene Therapy (2001-05), serving on the executive committee of the New York Academy of Medi-cine/Ellsberg Neurosurgery fellowship (200105), and being annual meeting president for the Association for Nervous and Mental Diseases in 2001. Goldman also has served as a member of the Children’s Neurobiological Solutions scientific advisory board and as a grant reviewer for the Wellcome Trust, the Volkswagen Foundation, the Israel-U.S. Binational Trust, the National Multiple Sclerosis Society, and the Christopher Reeve Paralysis Foundation.
Goldman, as a top specialist, has served as a consultant or an adviser for several organizations. His work as a consultant or adviser includes service with Merck Inc. (2003), the Merck Neuroscience Research Labs, Q Therapeutics (2003), Aven-tis Pharmaceuticals (2001-03), and Neuronyx Inc. (2001-02).
current research
Current projects being conducted by Goldman and his colleagues are extensive and include research into human oligodendrocyte progenitor molecular biology, human neural stem cell and progenitor gene expression and differential signaling, tumor stem and progenitor cells of the human central nervous system, induced neurogenesis in neurodegenerative disease, progenitor cell-based myelina-tion of congenitally dysmyelinated brain, relationship between angiogenesis and neurogenesis in the adult canary, regulation of astrocytosis from endogenous progenitors, and neural induction and therapeutic use of human ES cells.
Goldman is particularly recognized for his excellent contributions to the field of stem cell science. He has developed novel ways to isolate specific types of adult neural progenitor cells from human biopsy brain samples that involves sorting the cells using genetic markers, and then proving the cells can integrate and function within the living rodent brain. This work is paving the way for clinical trials using stem cells to treat diseases such as Parkinson’s and Multiple Sclerosis.
