Laboratory Values of Clinical Importance (Rheumatology) Part 3

TABLE A-2

CLINICAL CHEMISTRY AND IMMUNOLOGY

ANALYTE

SPECIMENa

SI UNITS

CONVENTIONAL UNITS

2-3 weeks postconception

75-2600IU/L

75-2600 mIU/mL

3-4 weeks postconception

850-20,800 IU/L

850-20,800 mIU/mL

4-5 weeks postconception

4000-100,200 IU/L

4000-100,200 mIU/mL

5-10 weeks postconception

11,500-289,000 IU/L

11,500-289,000 mIU/mL

10-14 weeks postconception

18,300-137,000 IU/L

18,300-137,000 mIU/mL

Second trimester

1400-53,000 IU/L

1400-53,000 mIU/mL

Third trimester

940-60,000 IU/L

940-60,000 mIU/mL

ß-Hydroxybutyrate

P

0-290 μ^^^

0-3 mg/dL

5-Hydroindoleacetic acid (5-HIAA)

U

10.5-36.6 μ^^^


2-7 mg/d

17-Hydroxyprogesterone (adult)

S

Male

0.15-7.5 nmol/L

5-250 ng/dL

Female

Follicular phase

0.6-3.0 nmol/L

20-100 ng/dL

Midcycle peak

3-7.5 nmol/L

100-250 ng/dL

Luteal phase

3-15 nmol/L

100-500 ng/dL

Postmenopausal

< 2.1 nmol/L

< 70 ng/dL

Hydroxyproline

U, 24 hour

38-500 μ^^^

38-500 μ^^^

Immunofixation

S

Not applicable

No bands detected

Immunoglobulin, quantitation (adult)

IgA

S

0.70-3.50 g/L

70-350 mg/dL

IgD

S

0-140 mg/L

0-14 mg/dL

IgE

S

24-430 μg/L

10-179 IU/mL

IgG

S

7.0-17.0 g/L

700-1700 mg/dL

IgG1

S

2.7-17.4 g/L

270-1740 mg/dL

IgG2

S

0.3-6.3 g/L

30-630 mg/dL

IgG3

S

0.13-3.2 g/L

13-320 mg/dL

IgG4

S

0.11-6.2 g/L

11-620 mg/dL

IgM

S

0.50-3.0 g/L

50-300 mg/dL

Insulin

S, P

14.35-143.5 pmol/L

2-20 μ^ιτ^

Iron

S

7-25 μ^^^

41-141 μg/dL

Iron-binding capacity

S

45-73 μ^^^

251-406 μg/dL

Iron-binding capacity saturation

S

0.16-0.35

16-35%

Joint fluid crystal

JF

Not applicable

No crystals seen

Joint fluid mucin

JF

Not applicable

Only type I mucin present

Ketone (acetone)

S, U

Negative

Negative

17 Ketosteroids

U

0.003-0.012 g/d

3-12 mg/d

Lactate

P, arterial

0.5-1.6 mmol/L

4.5-14.4 mg/dL

P, venous

0.5-2.2 mmol/L

4.5-19.8 mg/dL

Lactate dehydrogenase

S

2.0-3.8 μkat/L

115-221 U/L

Lactate dehydrogenase isoenzymes

S

Fraction 1 (of total)

0.14-0.26

14-26%

Fraction 2

0.29-0.39

29-39%

Fraction 3

0.20-0.25

20-25%

Fraction 4

0.08-0.16

8-16%

Fraction 5

0.06-0.16

6-16%

Lipase (method dependent)

S

0.51-0.73 μkat/L

3-43 U/L

Lipids: see Table A-5

Lipoprotein (a)

S

0-300 mg/L

0-30 mg/dL

Low-density lipoprotein (LDL) (see Table A-5)

Luteinizing hormone (LH)

S, P

Female

Menstruating:

Follicular phase

2.0-15.0 U/L

2.0-15.0 U/L

Ovulatory phase

22.0-105.0 U/L

22.0-105.0 U/L

Luteal phase

0.6-19.0 U/L

0.6-19.0 U/L

Postmenopausal

16.0-64.0 U/L

16.0-64.0 U/L

Male

2.0-12.0 U/L

2.0-12.0 U/L

TABLE A-2

CLINICAL CHEMISTRY AND IMMUNOLOGY

ANALYTE

SPECIMENa

SI UNITS

CONVENTIONAL UNITS

Magnesium

S

0.62-0.95 mmol/L

1.5-2.3 mg/dL

Metanephrine

P

<0.5 nmol/L

<100 pg/mL

Metanephrine

U

30-211 mmol/mol creatinine

53-367 μg/g creatinine

Methemoglobin

WB

0.0-0.01

0-1%

Microalbumin urine

U

24-h urine

0.0-0.03 g/d

0-30 mg/24 h

Spot urine

0.0-0.03 g/g creatinine

0-30 μg/mg creatinine

Myoglobin

S

Male

19-92 μg/L

19-92 μg/L

Female

12-76 μg/L

12-76 μg/L

Norepinephrine

U

89-473 nmol/d

15-80 μg/d

Norepinephrine

P

Supine (30 min)

650-2423 pmol/L

110-410 pg/mL

Sitting

709-4019 pmol/L

120-680 pg/mL

Standing (30 min)

739-4137 pmol/L

125-700 pg/mL

N-telopeptide (cross linked), NTx

S

Female, premenopausal

6.2-19.0 nmol BCE

6.2-19.0 nmol BCE

Male

5.4-24.2 nmol BCE

5.4-24.2 nmol BCE

Bone collagen equivalent (BCE)

N-telopeptide (cross linked), NTx

U

Female, premenopausal

17-94 nmol BCE/mmol creatinine

17-94 nmol BCE/mmol creatinine

Female, postmenopausal

26-124 nmol BCE/mmol creatinine

26-124 nmol BCE/mmol creatinine

Male

21-83 nmol BCE/mmol

21-83 nmol BCE/mmol

creatinine

creatinine

Bone collagen equivalent (BCE)

5′ Nucleotidase

S

0.02-0.19 μkat/L

0-11 U/L

Osmolality

P

275-295 mosmol/kg serum water

275-295 mosmol/kg serum water

U

500-800 mosmol/kg

500-800 mosmol/kg

water

water

Osteocalcin

S

11-50 μg/L

11-50 ng/mL

Oxygen content

WB

Arterial (sea level)

17-21

17-21 vol%

Venous (sea level)

10-16

10-16 vol%

Oxygen percent saturation (sea level)

WB

Arterial

0.97

94-100%

Venous, arm

0.60-0.85

60-85%

Parathyroid hormone (intact)

S

8-51 ng/L

8-51 pg/mL

Phosphatase, alkaline

S

0.56-1.63 μkat/L

33-96 U/L

Phosphorus, inorganic

S

0.81-1.4 mmol/L

2.5-4.3 mg/dL

Porphobilinogen

U

None

None

Potassium

S

3.5-5.0 mmol/L

3.5-5.0 meq/L

Prealbumin

S

170-340 mg/L

17-34 mg/dL

Progesterone

S, P

Female

Follicular

<3.18 nmol/L

<1.0 ng/mL

Midluteal

9.54-63.6 nmol/L

3-20 ng/mL

Male

<3.18 nmol/L

<1.0 ng/mL

Prolactin

S

0-20 μg/L

0-20 ng/mL

Prostate-specific antigen (PSA)

S

Male

<40 years

0.0-2.0 μg/L

0.0-2.0 ng/mL

>40 years

0.0-4.0 μg/L

0.0-4.0 ng/mL

TABLE A-2

CLINICAL CHEMISTRY AND IMMUNOLOGY

ANALYTE

SPECIMENa

SI UNITS

CONVENTIONAL UNITS

PSA, free; in males 45-75 years, with

S

>0.25 associated with

>25% associated with

PSA values between 4 and 20 μg/mL

benign prostatic hyperplasia

benign prostatic hyperplasia

Protein fractions

S

Albumin

35-55 g/L

3.5-5.5 g/dL (50-60%)

Globulin

20-35 g/L

2.0-3.5 g/dL (40-50%)

Alpha1

2-4 g/L

0.2-0.4 g/dL (4.2-7.2%

Alpha2

5-9 g/L

0.5-0.9 g/dL (6.8-12%

Beta

6-11 g/L

0.6-1.1 g/dL (9.3-15%

Gamma

7-17 g/L

0.7-1.7 g/dL (13-23%)

Protein, total

S

67-86 g/L

6.7-8.6 g/dL

Pyruvate

P, arterial

40-130 μmol/L

0.35-1.14 mg/dL

P, venous

40-130 μmol/L

0.35-1.14 mg/dL

Rheumatoid factor

S, JF

<30 kIU/L

<30 IU/mL

Serotonin

WB

0.28-1.14 μ(^^

50-200 ng/mL

Serum protein electrophoresis

S

Not applicable

Normal pattern

Sex hormone binding globulin (adult)

S

Male

13-71 nmol/L

13-71 nmol/L

Female

18-114 nmol/L

18-114 nmol/L

Sodium

S

136-146 mmol/L

136-146 meq/L

Somatomedin-C (IGF-1) (adult)

S

16-24 years

182-780 μg/L

182-780 ng/mL

25-39 years

114-492 μg/L

114-492 ng/mL

40-54 years

90-360 μg/L

90-360 ng/mL

>54 years

71-290 μg/L

71-290 ng/mL

Somatostatin

P

<25 ng/L

<25 pg/mL

Testosterone, total, morning sample

S

Female

0.21-2.98 nmol/L

6-86 ng/dL

Male

9.36-37.10 nmol/L

270-1070 ng/dL

Thyroglobulin

S

0.5-53 μg/L

0.5-53 ng/mL

Thyroid-binding globulin

S

13-30 mg/L

1.3-3.0 mg/dL

Thyroid-stimulating hormone

S

0.34-4.25 mIU/L

0.34-4.25 ^U/mL

Thyroxine, free (fT4)

S

10.3-21.9 pmol/L

0.8-1.7 ng/dL

Thyroxine, total (T4)

S

70-151 nmol/L

5.4-11.7 μg/dL

(Free) thyroxine index

S

6.7-10.9

6.7-10.9

Transferrin

S

2.0-4.0 g/L

200-400 mg/dL

Triglycerides (see Table A-5)

S

0.34-2.26 mmol/L

30-200 mg/dL

Triiodothyronine, free (fT3)

S

3.7-6.5 pmol/L

2.4-4.2 pg/mL

Triiodothyronine, total (T3)

S

1.2-2.1 nmol/L

77-135 ng/dL

Troponin I

S

Normal population, 99 %tile

0-0.08 μg/L

0-0.08 ng/mL

Cut-off for MI

>0.4 μg/L

>0.4 ng/mL

Troponin T

S

Normal population, 99 %tile

0-0.1 μg/L

0-0.01 ng/mL

Cut-off for MI

0-0.1 μg/L

0-0.1 ng/mL

Urea nitrogen

S

2.5-7.1 mmol/L

7-20 mg/dL

Uric acid

S

Females

0.15-0.33 μmol/L

2.5-5.6 mg/dL

Males

0.18-0.41 μmol/L

3.1-7.0 mg/dL

Urobilinogen

U

0.09-4.2 μmol/d

0.05-25 mg/24 h

Vanillylmandelic acid (VMA)

U, 24h

<30 μmol/d

<6 mg/d

Vasoactive intestinal polypeptide

P

0-60 ng/L

0-60 pg/mL

aP, plasma; S, serum; U, urine; WB, whole blood; JF, joint fluid.

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