edema (Parkinson’s disease)

Fluid (water) retention that causes swelling. Edema is a common side effect of several dopamine agonist medications taken to relieve the motor symptoms of Parkinson’s disease, in particular pergolide (Permax), pramipexole (Mirapex), and ropinerole (Requip). Most often, edema is mild and most noticeable in the ankles and feet, although it often affects the hands and sometimes the face as well. Mild edema is not usually a health problem and may not even be apparent to the person with Parkinson’s. Edema significant enough to cause shoes or rings to become tight requires a doctor’s attention to confirm that it is not a symptom of other health problems such as heart disease, liver disease, and kidney disease. if it is a side effect of medications, a neurologist’s input often is helpful in making the decision as to whether the motor benefits of the medication outweigh the irritation of having the edema. Walking, standing for a few minutes during periods of prolonged sitting, and elevating the legs and feet when sitting help minimize edema.