Biology Reference
In-Depth Information
Kenney, D., Cairns, L., Remold-O'Donnell, E., Peterson, J., et al., 1986. Morphological
abnormalities in the lymphocytes of patients with the Wiskott-Aldrich syndrome. Blood
68: 1329-1332.
Krugmann, S., Jordens, I., Gevaert, K., Driessens, M., et al., 2001. Cdc42 induces filopodia
by promoting the formation of an IRSp53:Mena complex. Curr. Biol. 11: 1645-1655.
Miki, H. and Takenawa, T., 1998. Direct binding of the verprolin-homology domain in N-
WASP to actin is essential for cytoskeletal reorganization. Biochem. Biophys. Res.
Commun. 243: 73-78.
Miki, H. and Takenawa, T., 2002. WAVE2 serves a functional partner of IRSp53 by
regulating its interaction with Rac. Biochem. Biophys. Res. Commun. 293: 93-99.
Miki, H., Miura, K. and Takenawa, T., 1996. N-WASP, a novel actin-depolymerizing
protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner
downstream of tyrosine kinases. EMBO J. 15: 5326-5335.
Miki, H., Sasaki, T., Takai, Y. and Takenawa, T., 1998a. Induction of filopodium
formation by WASP-related actin-depolymerizing protein N-WASP. Nature 391: 93-96.
Miki, H., Suetsugu, S. and Takenawa, T., 1998b. WAVE, a novel WASP-family protein
involved in actin reorganization induced by Rac. EMBO J. 17: 6932-6941.
Miki, H., Yamaguchi, H., Suetsugu, S. and Takenawa, T., 2000. IRSp53 is an essential
intermediate between Rac and WAVE in the regulation of membrane ruing. Nature
408: 732-735.
Mizutani, K., Miki, H., He, H., Maruta, H. and Takenawa, T., 2002. Essential role of
neural Wiskott-Aldrich syndrome protein in podosome formation and degradation of
extracellular matrix in src-transformed fibroblasts. Cancer Res. 62: 669-674.
Molina, I. J., Kenney, D. M., Rosen, F. S. and Remold-O'Donnell, E., 1992. T cell lines
characterize events in the pathogenesis of the Wiskott-Aldrich syndrome. J. Exp. Med.
176: 867-874.
Rohatgi, R., Ma, L., Miki, H., Lopez, M., et al., 1999. The interaction between N-WASP
and the Arp2/3 complex links Cdc42-dependent signals to actin assembly. Cell 97: 221-
231.
Rohatgi, R., Nollau, P., Ho, H. Y., Kirschner, M. W. and Mayer, B. J., 2001. Nck and
phosphatidylinositol 4,5-bisphosphate synergistically activate actin polymerization
through the N-WASP-Arp2/3 pathway. J. Biol. Chem. 276: 26448-26452.
Suetsugu, S., Miki, H. and Takenawa, T., 1998. The essential role of profilin in the
assembly of actin for microspike formation. EMBO J. 17: 6516-6526.
Suetsugu, S., Miki, H. and Takenawa, T., 1999. Identification of two human WAVE/
SCAR homologues as general actin regulatory molecules which associate with Arp2/3
complex. Biochem. Biophys. Res. Commun. 260: 296-302.
Suetsugu, S., Miki, H. and Takenawa, T., 2001. Identification of another Actin-related
protein (Arp) 2/3 complex binding site in Neural Wiskott-Aldrich syndrome protein
(N-WASP), that complements actin polymerization induced by the Arp2/3 complex
activating (VCA) domain of N-WASP. J. Biol. Chem. 276: 33175-33180.
Suetsugu, S., Miki, H. and Takenawa, T., 2002. Spatial and temporal regulation of actin
polymerization for cytoskeleton formation through Arp2/3 complex and WASP/WAVE
proteins. Cell Motil. Cytoskeleton 51: 113-122.
Symons, M., Derry, J. M., Karlak, B., Jiang, S., et al., 1996. Wiskott-Aldrich syndrome
protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization.
Cell 84: 723-734.
Wear, M. A., Schafer, D. A. and Cooper, J. A., 2000. Actin dynamics: assembly and
disassembly of actin networks. Curr. Biol. 10: R891-895.
