Chemistry Reference
In-Depth Information
Table 1.2
(continued)
Molecular dyes or enzymatic reactions
Analyte
Dynamic range
Sensitivity/
detection Limit
Reference
Electrochemiluminescence
2-(dibutylamino)-ethanol
3
μ
M
10 mM
0.9
µ
M
[
123
]
-
Nicotinamide adenine
dinucleotide
0.2
-
20.0 mM
72
µ
M
[
123
]
100 ng or U mL
−
1
0.15 ng mL
−
1
, 0.6
and 0.17 U mL
−
1
,
0.5 ng mL
−
1
Tumour markers (AFP,
CA125, CA199, CEA)
5
[
103
,
124
,
125
]
-
10 ng mL
−
1
1fgmL
−
1
Carcinoembryonic antigens
0.01
[
126
]
-
Dopamine
1
µ
M
-
10 mM
1
µ
M
[
127
]
Pb
2+
ions
<2
µ
M
10 pM
[
128
]
Hg
2+
ions
<2
µ
M
0.2 nM
[
128
]
Enzo[a]-pyrene (B[a]P)
0.15
12.5
µ
M
150 nM
[
129
]
-
*
Chemiluminescence
Glucose
50 mM L
−
1
0.14 mmol L
−
1
2.5
[
130
]
-
50 mM L
−
1
0.52 mmol L
−
1
Uric acid
2.5
[
130
,
131
]
-
1.0 ng mL
−
1
, 0.4,
and 0.06 U mL
−
1
and 0.02 ng mL
−
1
Tumour markers (AFP,
CA153, CA199, CEA)
<150 mM ng or U
mL
−
1
[
102
,
132
]
Fluorescence
Fluorescein isothiocyanate-
labeled bovine serum albumin
0.1
100 pmol
125 fmol
[
133
]
-
DNA
10
10,000 pM
100 pM
[
134
]
-
Nucleic acids
0.08
-
5.00
µ
M
1,200 input
templates
[
135
]
Lung cancer associated
miRNA
10 nM
10
µ
M
100 nM
[
136
]
-
*
Nucleic acid hybridisation
1
5 pmol
300 fmol
[
137
]
-
Asian soybean rust
0.0032
-
3.2 mg/mL
2.2 ng/mL
[
138
]
Dual electrochemical/colorimetric sensing
Au(III)
1
200 ppm
1 ppm
[
139
]
-
Bacterial whole-cell
Bacterial quorum signalling
molecules
-
N-acylhomoserine
lactones
10
−
9
-
10
−
4
M
10
8
M
[
140
]