Chemistry Reference
In-Depth Information
Table 1.2 (continued)
Molecular dyes or enzymatic reactions
Analyte
Dynamic range
Sensitivity/
detection Limit
Reference
Electrochemiluminescence
2-(dibutylamino)-ethanol
3
μ
M
10 mM
0.9
µ
M
[ 123 ]
-
Nicotinamide adenine
dinucleotide
0.2 - 20.0 mM
72 µ M
[ 123 ]
100 ng or U mL 1
0.15 ng mL 1 , 0.6
and 0.17 U mL 1 ,
0.5 ng mL 1
Tumour markers (AFP,
CA125, CA199, CEA)
5
[ 103 , 124 ,
125 ]
-
10 ng mL 1
1fgmL 1
Carcinoembryonic antigens
0.01
[ 126 ]
-
Dopamine
1 µ M - 10 mM
1 µ M
[ 127 ]
Pb 2+ ions
<2 µ M
10 pM
[ 128 ]
Hg 2+ ions
<2
µ
M
0.2 nM
[ 128 ]
Enzo[a]-pyrene (B[a]P)
0.15
12.5
µ
M
150 nM
[ 129 ]
-
*
Chemiluminescence
Glucose
50 mM L 1
0.14 mmol L 1
2.5
[ 130 ]
-
50 mM L 1
0.52 mmol L 1
Uric acid
2.5
[ 130 , 131 ]
-
1.0 ng mL 1 , 0.4,
and 0.06 U mL 1
and 0.02 ng mL 1
Tumour markers (AFP,
CA153, CA199, CEA)
<150 mM ng or U
mL 1
[ 102 , 132 ]
Fluorescence
Fluorescein isothiocyanate-
labeled bovine serum albumin
0.1
100 pmol
125 fmol
[ 133 ]
-
DNA
10
10,000 pM
100 pM
[ 134 ]
-
Nucleic acids
0.08 - 5.00 µ M
1,200 input
templates
[ 135 ]
Lung cancer associated
miRNA
10 nM
10
µ
M
100 nM
[ 136 ]
-
*
Nucleic acid hybridisation
1
5 pmol
300 fmol
[ 137 ]
-
Asian soybean rust
0.0032 - 3.2 mg/mL
2.2 ng/mL
[ 138 ]
Dual electrochemical/colorimetric sensing
Au(III)
1
200 ppm
1 ppm
[ 139 ]
-
Bacterial whole-cell
Bacterial quorum signalling
molecules - N-acylhomoserine
lactones
10 9
- 10 4 M
10 8 M
[ 140 ]
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