Chemistry Reference
In-Depth Information
silicon amino acids holds great promise for maintaining biological activity while
simultaneously suppressing the rapid degradation of peptides in vivo (see Fig. 8.9 ).
The growing commercial availability of silicon containing amino acids will help
fuel that process.
The more recent silanediol peptidomimetics, which act as inhibitors of hydrolase
enzymes, are expected to see much more development as their properties and ap-
plications continue to be explored.
References
1. Birkofer L, Ritter A (1956) Angew Chem 68:461-462
2. Mortensen M, Husmann R, Veri E, Bolm C (2009) Chem Soc Rev 38:1002-1010
3. Cavelier F, Vivet B, Martinez J, Aubry A, Didierjean C, Vicherat A, Marraud M (2002) J Am
Chem Soc 124:2917-2923
4. Liu G, Sieburth SMcN (2005) Org Lett 7:665-668
5. Sun H, Martin C, Kesselring D, Keller R, Moeller KD (2006) J Am Chem Soc 128:13761-
13771
6. Sun H, Moeller KD (2003) Org Lett 5:3189-3192
7. Sun H, Moeller KD (2002) Org Lett 4:1547-1550
8. Fessenden RJ, Fessenden JS (1967) Adv Drug Res 4:95-132
9. Tacke R, Wannagat U (1979) Top Curr Chem 84:1-75
10. Fessenden RJ, Fessenden JS (1980) Adv Organomet Chem 18:275-299
11. Barcza S (1988) In: Corey ER, Corey JY, Gaspar P (eds) The value and new directions of
silicon chemistry for obtaining bioactive compounds in silicon chemistry. Wiley, New York,
pp 135-144
12. Tacke R, Linoh H (1989) In: Patai S, Rappoport Z (eds) Bioorganosilicon chemistry in the
chemistry of organic silicon compounds. Wiley, New York, pp 1143-1206
13. Bains W, Tacke R (2003) Curr Opin Drug Discov Dev 6:526-543
14. Mills JS, Showell GA (2004) Expert Opin Investig Drugs 13:1149-1157
15. Englebienne P, Hoonacker AV, Herst CV (2005) Drug Des Rev Online 10:654-671
16. Sieburth SMcN (2008) Bioactive organosilanes in gelest catalog. pp 76-83.
17. Lazareva LF (2011) Russ Chem Bull Int Ed 60:615-632
18. Fessenden RJ, Hartman RA (1970) J Med Chem 13:52-54
19. Fleming I, Dunoguès J, Smithers R (2004) The electrophilic substitution of allylsilanes and
vinylsilanes in organic reactions. Wiley, New York (1989), 37:57-575
20.
Franz AK, Woerpel KA (2000) Acc Chem Res 33:813-820
21.
Denmark SE, Wehrli D, Choi JY (2000) Org Lett 2:2491-2494
22.
Sunderhaus JD, Lam H, Dudley GB (2003) Org Lett 5:4571-4573
23.
Ottosson H, Steel PG (2006) Chemistry 12:1576-1585
24.
Brändström A (1959) Acat Chem Scand 13:619-622
25.
Woo DV, Christian JE, Schnell RC (1979) Can J Pharm Sci 14:12-14
26.
Ohshita J, Tokunaga Y, Sakurai H, Kunai A (1999) J Am Chem Soc 121:6080-6081
27.
Tacke R, Popp F, Müller B, Theis B, Burschka C, Hamacher A, Kassack MU, Schepmann D,
Wünsch B, Jurva U, Wellner E (2008) Chem Med Chem 3:152-164
28.
Tacke R, Heinrich T, Bertermann R, Burschka C, Hamacher A, Kassack MU (2004) Organo-
metallics 23:4468-4477
29.
Johansson T, Weidolf L, Popp F, Tacke R, Jurva U (2010) Drug Metab Disp 38:73-83
30.
Bolm C, Kasyan A, Drauz K, Günther K, Raabe G (2000) Angew Chem Int Ed 39:2288-2290
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