Chemistry Reference
In-Depth Information
Fig. 8.22
Reverse-aza-Brook rearrangement of
N
-silyl carbamates
Fig. 8.23
Sulfinimines undergo addition of silyl anions with high diastereoselectivity
8.6
Future Prospects
Silicon, with its close relationship to carbon, will continue to be a part of the in-
novation in bio-active substance design and development. As the pharmaceutical
industry moves more and more into peptide and protein based therapies, silicon-
containing amino acids and peptides will be part of those investigations. Use of the
