Biomedical Engineering Reference
In-Depth Information
[35]
Spencer, E., Jiang, J., and Chen, Z.J., Signal-induced ubiquitination of IκBα by the
F-box protein Slimb/βTrCP,
Genes Dev.,
13, 284, 1999.
[36]
Hattori, K., Hatakeyama, S., Shirane, M. et al
.
, Molecular dissection of the interac-
tions among IkappaBalpha, FWD1, and Skp1 required for ubiquitin-mediated pro-
teolysis of IkappaBalpha,
J. Biol. Chem.,
274, 29641, 1999.
[37]
Kroll, M., Margottin, F., Kohl, A. et al
.
, Inducible degradation of IκBα by the
proteasome requires interaction with the F-box protein h-βTrCP,
J. Biol. Chem.,
274,
7941, 1999.
[38]
Baldi, L., Brown, K., Franzoso, G.
et al
.
, Critical role for lysines 21 and 22 in signal-
induced, ubiquitin-mediated proteolysis of IkappaBalpha,
J. Biol. Chem.,
271, 376, 1996.
[39]
Petroski, M.D. and Deshaies, R.J., Context of multiubiquitin chain attachment influ-
ences the rate of Sic1 degradation,
Mol. Cell,
11, 1435, 2003.
[40]
Neish, A.S., Gewirtz, A.T., Zeng, H.
et al
.
, Prokaryotic regulation of epithelial
responses by inhibition of IκBα ubiquitination,
Science,
289, 1560, 2000.
[41]
Peng, J., Schwartz, D., Elias, J.E. et al
.
, A proteomics approach to understanding
protein ubiquitination,
Nat Biotechnol,
21, 921, 2003.
[42]
Ben-Neriah, Y., Regulatory functions of ubiquitination in the immune system,
Nature
Immunol.,
3, 20, 2002.
[43]
Orlicky, S., Tang, X., Willems, A. et al
.
, Structural basis for phosphodependent sub-
strate selection and orientation by the SCFCdc4 ubiquitin ligase,
Cell,
112, 243, 2003.
[44]
Neer, E.J., Schmidt, C.J., Nambudripad, R. et al
.
, The ancient regulatory-protein
family of WD-repeat proteins,
Nature,
371, 297, 1994.
[45]
Busino, L., Donzelli, M., Chiesa, M. et al
.
, Degradation of Cdc25A by βTrCP during
S phase and in response to DNA damage,
Nature,
426, 87, 2003.
[46]
Davis, M., Hatzubai, A., Anderson, J.S.
et al., Pseudosubstrate regulation of the
SCF(βTrCP) ubiquitin ligase by hnRNP-U,
Genes Dev.,
16, 439, 2002.
[47]
Kanemori, Y., Uto, K., and Sagata, N., βTrCP recognizes a previously undescribed
nonphosphorylated destruction motif in Cdc25A and Cdc25B phosphatases,
Proc.
Natl. Acad. Sci. USA,
102, 6279, 2005.
[48]
Chiaur, D.S., Murthy, S., Cenciarelli, C.
et al
.
, Five human genes encoding F-box
proteins: Chromosome mapping and analysis in human tumors,
Cytogenet Cell Genet,
88, 255, 2000.
[49]
Nakayama, K., Hatakeyama, S., Maruyama, S. et al
.
, Impaired degradation of inhib-
itory subunit of NF-κB (IκB) and β-catenin as a result of targeted disruption of the
βTrCP1 gene,
Proc. Natl. Acad. Sci. USA,
100, 8752, 2003.
[50]
Guardavaccaro, D., Kudo, Y., Boulaire, J.
et al
.
, Control of meiotic and mitotic
progression by the F box protein βTrCP1
in vivo,
Dev. Cell,
4, 799, 2003.
[51]
Kafri, R., Bar-Even, A., and Pilpel, Y., Transcription control reprogramming in genetic
backup circuits,
Nat. Genet.,
37, 295, 2005.
[52]
Campbell, K.J., Rocha, S., and Perkins, N.D., Active repression of anti-apoptotic
gene expression by RelA (p65) NF-κB,
Mol. Cell,
13, 853, 2004.
[53]
Huang, T.T., Wuerzberger-Davis, S.M., Seufzer, B.J. et al
.
, NF-κB activation by
camptothecin: A linkage between nuclear DNA damage and cytoplasmic signaling
events,
J. Biol. Chem.,
275, 9501, 2000.
[54]
Huang, T.T., Feinberg, S.L., Suryanarayanan, S. et al
.
, The zinc finger domain of
NEMO is selectively required for NF-κB activation by UV radiation and topoi-
somerase inhibitors,
Mol. Cell Biol.,
22, 5813, 2002.
[55]
Huang, D.B., Wuerzberger-Davis, S.M., Wu, Z.-H.
et al
.
, Sequential modification of
NEMO/IKKγ by SUMO-1 and ubiquitin mediates NF-κB activation by genotoxic
shock,
Cell,
115, 565, 2003.