Biology Reference
In-Depth Information
Phases
Minutes
I 0 - 5
II 5 - 120
III 120 - 360
IV 360 - 450
V 450 - 850
I
V
TL
IV
II
III
0 5
120
360
450
850
Time, min
b
Transistion or Activated State
G
‡
DG
2
‡
G
-1
‡
D
2
2
I
1
1
G
II
IV
0
0
-1
-1
V
-2
-2
III
Transcriptosome (T) Degradosome (D)
Quantum States Quantum States
c
The quantum states of the TD complexes and their effect ts on dTL/dt
Degradosome
-2
-1
0
1
2
-2
0
-1
-2
-3
-4
-1
1
0
-1
-2
-3
0
2
1
0
-1
-2
1
3
2
1
0
-1
2
4
3
2
1
0
Fig. 12.30 The interpretation of the RNA trajectories in terms of the quantum states of the
underlying transcriptosomes and degradosomes. (a) The five phases of the typical RNA trajectory
(or the kinetics of TL, transcript level) of budding yeast after replacing glucose with galactose
at
t
0. (b) The five quantum states each postulated for the transcriptosome (T) and degradosome
(D) constituting a TD complex that determines the shape of an RNA trajectory. (c) all possible
quantum states for a TD complex and their effects on the shape of an RNA trajectory, i.e., on dTL/dt
¼
