MAMMALIAN OLIGOPEPTIDE TRANSPORTERS - Drug Transporters: Molecular Characterization and Role in Drug Disposition - page 137

70. Adibi, S.A. (1997). The oligopeptide transporter (PepT1) in human intestine: biology and
function. Gastroenterology 113:322-340.
71. Nussberger, S., Steel, A., Trott, D., Romero, M., Boron, W.F., and Hediger, M. (1997).
Symmetry of H + binding to the intra- and extracellular side of the H + -coupled oligopep-
tide cotransporter PepT1. J. Biol. Chem. 272:7777-7785.
72. Kennedy, D.J., Leibach, F.H., Ganapathy, V., and Thwaites, D.T. (2002). Optimal ab-
sorptive transport of the dipeptide glycylsarcosine is dependent on functional Na + /H +
exchange activity. Pflugers Arch. Eur. J. Physiol. 445(1):139-146.
73. Thwaites, D.T., Kennedy, D.J., Raldua, D., Anderson, C.M., Mendoza, M.E., Bladen,
C.L., and Simmons, N.L. (2002). H/dipeptide absorption across the human intestinal
epithelium is controlled indirectly via a functional Na/H exchanger. Gastroenterology
122(5):1322-1333.
74. Temple, C.S., Bronk, J.K., Bailey, P.D., and Boyd, C.A. (1995). Substrate charge de-
pendence of stoichiometry shows membrane potential is driving force for proton-
peptide cotransport in rat renal cortex. Pflugers Arch. Eur. J. Physiol. 430:825-
829.
75. Temple, C.S., Bailey, P.D., Bronk, J.R., and Boyd, C.A.R. (1996). A model for the kinetics
of neutral and anionic dipeptide-proton cotransport by the apical membrane of rat kidney
cortex. J. Physiol. 494(3):795-808.
76. Amasheh, S., Wenzel, U., Boll, M., Dom, D., Weber, W., and Clauss, W.D.H. (1997).
Transport of charged dipeptides by the intestinal H + /peptide symporter PepT1 expressed
in Xenopus laevis oocytes. J. Membr. Biol. 155:247-256.
77. Balimane, P.V., and Sinko, P.J. (2000). Effect of ionization on the variable uptake of vala-
cyclovir via the human intestinal peptide transporter (hPepT1) in CHO cells. Biopharm.
Drug Dispos. 21:165-174.
78. Kottra, G., Stamfort, A., and Daniel, H. (2002). PEPT1 as a paradigm for membrane
carriers that mediate electrogenic bidirectional transport of anionic, cationic and neutral
substrates. J. Biol. Chem. 277(36):32683-32691.
79. Wenzel, U., Gebert, I., Weintraut, H., Weber, W.-M., Clauss, W., and Daniel, H. (1996).
Transport characteristics of differently charged cephalosporin antibiotics in oocytes ex-
pressing the cloned intestinal peptide transporter PepT1 and in human intestinal Caco-2
cells. J. Pharmacol. Exp. Ther. 277:831-839.
80. Mackenzie, B., Loo, D.D.F., Fei, Y.-F., Liu, W., Ganapathy, V., Leibach, F.H., and Wright,
E.M. (1996). Mechanisms of the human intestinal H + -coupled oligopeptide transporter
hPEPT1. J. Biol. Chem. 271(10):5430-5437.
81. Irie, M., Terada, T., Katsura, T., Matsuoka, S., and Inui, K.-I. (2005). Computational
modelling of H + -coupled peptide transport via human PEPT1. J. Physiol. 565:429-
439.
82. Bolger, M.B., Haworth, I.S., Yeung, A.K., Ann, D., von Grafenstein, H., Hamm-Alvarez,
S., Okamoto, C.T., Kim, K.J., Basu, S.K., Wu, S., and Lee, V.H. (1998). Structure, func-
tion, and molecular modeling approaches to the study of the intestinal dipeptides trans-
porter PepT1. J. Pharm. Sci. 87:1286-1291.
83. Yeung, A.K., Basu, S.K., Wu, S., Chu, C., Okamoto, C.T., Hamm-Alvarez, S., von
Grafenstein, H., Shen, W.C., Kim, K.J., Bolger, M.B., et al. (1998). Molecular iden-
tification of a role for tyrosine 167 in the function of the human intestinal proton-
coupled dipeptide transporter (hPepT1). Biochem. Biophys. Res. Commun. 250:103-
107.