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tics in order to reconstruct, visualize and analyze huge numbers of noisy biological
and medical images with high accuracy and e ciency in the future.
Acknowledgement. he author would like to thank previous collaborators in this area, in-
cluding Dr. Chung-Ming Chen, Jyh-Cheng Chen, Han-Ming Wu, Tai-Been Chen and others.
He is also thankful for the comments from Dr. Josh Rest and the editors that subsequently
helped him to improve this report.
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