Biomedical Engineering Reference
In-Depth Information
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17.6 Pore size distribution in cross-linked PLA porous scaffolds: Lait-X/
b and Lait-X/c. Reprinted with permission from Wiley-VCH (Sakai et al.,
2012).
solvent crystallized and the polymer was expelled from the solvent
crystallization front. Solvent crystals formed pores after subsequent
sublimation. To better mimic the mineral component and the microstructure
of natural bone, novel nHA nanocomposite scaffolds with high porosity and
well-controlled pore architectures were prepared using the TIPS techniques
(Fig. 17.2 (Nejati et al., 2008)). The incorporation of nHA particles into
PLLA solution perturbed the solvent crystallization to some extent and
thereby made the pore structure more irregular and isotropic. The
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