Biomedical Engineering Reference
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where Q k = ( Q k ; Q k ) and g k = ( Q k+1 ; Q k+1 ), and set L m+2 (Q m+2 ) =
L m+2;0 ( Q 0 m+2 ) + L m+2;1 ( Q 1 m+2 ), with Q m+2 = ( Q 0 m+2 ; Q 1 m+2 ). In addition,
the log-likelihood loss, defined as L V (Q V ) = log Q V , will be used for com-
ponent Q V of Q. For each k 2f0; 1;:::;m + 2g, given component
Q k , we may
define the fluctuation
!
h 1 (a;v)
Q k1
r=0 g r (a)(o)
Q k ( k;a )(o) = expit
Q k (o) + k
logit
and corresponding fluctuation sub-model Q k ( Q k ) = f Q k ( k;a ) : j k;a j < 1g,
where we have dened
h 1 (a;v) = h(a;v) (z 1 (a;v);z 2 (a;v);:::;z R (a;v)) :
In this set of fluctuation sub-models, the fluctuation parameter k is common
to both Q k ( Q k ) and Q k ( Q k ); a typical member of the joint fluctuation sub-
model will be denoted by Q k ( k ) = ( Q k ( k ); Q k ( k )). Any fluctuation sub-
model for Q V with parameter V and score
X
h 1 (a;V ) Q 0 (V ) m (Q) (a;V )
D V (O) =
a2f0;1g
at V = 0 can be selected. We can verify then that, for k 2f0; 1;:::;m + 1g,
d
d k L k (Q k ( k ); g k ) = D k ;
where we have that
X
Q k+1 Q k :
I( A(k 1) = a 0;a (k 1)) h 1 (a;V )
D k (O) =
Q k1
r=0 g r (a)
a2f0;1g
With D m+2 defined similarly, we also find that
d
d m+2 L m+2 (Q m+2 ( m+2 )) = D m+2 :
The ecient influence curve D of can be shown to be
" @
@ E (D )
# 1
=(P 0 )
D =
D
 
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