Biomedical Engineering Reference
In-Depth Information
(A)
(B)
(C)
(D)
(E)
(F)
FIGURE 6.10
SEM micrographs of dentin
adhesive interfaces. (A) SBMP control (P
primer, A
adhesive), (B) P
NAg,
5
5
1
A
20NACP at a higher
magnification, and (E, F) at even higher magnifications. Adhesives filled the dentinal tubules and formed
resin tags “T” for all six groups. “HL” indicates the hybrid layer between the adhesive and the underlying
mineralized dentin. (D
NAg
20NACP, (C) P
NAg, A
NAg
40NACP. (D) P
NAg, A
NAg
1
1
1
1
1
1
1
1
F) Numerous NACP nanoparticles were present in the adhesive layer, in the hybrid
zone, and inside the dentinal tubules. Arrows in (D
F) indicate NACP in the dentinal tubules. NACP were
able to infiltrate with the adhesive not only into straight tubules (E) but also into bent and irregularly-shaped
tubules (F).
Adapted from Ref.
[57]
with permission.
6.7
Summary and conclusions
Novel calcium phosphate nanoparticles and antibacterial monomers were synthesized, and a new class
of bioactive nanocomposites and nanostructured adhesives with a combination of antibacterial and
remineralizing capabilities were developed for the first time. The novel NACP
QADM nanocompo-
site had a strong antibacterial activity that was maintained after water-aging for 6 months. Strength
