Biomedical Engineering Reference
In-Depth Information
A
B
C
D
100 µm
COLOR FIGURE 6.1
Fluorescence.imaging.(10×).of.CD4.cells.captured.in.a.nanobiochip..(A).Cells.are.labeled.with.anti-CD4.antibody.
conjugated.with.Qdot.565.(in.green)..(B).Cells.are.labeled.with.anti-CD3
+
.antibody.conjugated.with.Qdot.655.(in.
red)..(C).CD3
+
CD4
+
.cells.are.shown.in.yellow.in.the.emerged.image..(d).Absolute.CD4.cell.count.(in.yellow).is.
obtained.in.the.processed.picture,.in.which.cells.in.red.or.green.are.deleted..A.long-pass.emission.ilter.allows.
for.CD4
+
.T.lymphocyte.counting.instead.of.image.processing..Boxes.on.the.right.in.each.panel.show.magniied.
images.from.the.left.(2×).
(Adapted.from.Jokerst,.J.V.,.et.al.,.
Lab Chip
,
8(12),.2079-2090,.2008.)
Bound nanoviricide
TM
lipid fusion with
virus particle
Bound nanoviricide
TM
wrapping onto
virus particle
2
3
4
A nanoviricide
TM
A virus particle destroyed
by a nanoviricide
TM
1
A nanoviricide
TM
binds to a
virus particle
COLOR FIGURE 7.2
Graphic.representation.of.the.mechanism.of.action.of.nanoviricide.binding.and.inactivation.of.viruses.
