Biomedical Engineering Reference
In-Depth Information
TABLE 10.2
Nano/Microibrous.Textures.Used.for.Nerve.Tissue.Engineering
Polymer
Concentration/
Composition/Solvent
InVitro
Studies:
CellType
InVivo
Studies:
NerveInjuryModel
PolymerType
FiberDiameter
Reference
FibersFabricatedby
Electrospinning
Laminin
3-8%.w/v
HFP
90-300.nm.(RF)
Human.adipose.stem.
cells.and.PC12.cells
—
Neal.et.al.,.2009
Laminin-PLLA.blend
10%.w/v;.1:250,.w:w
HFP
100-500.nm.(RF)
Rat.PC12.cells
—
Koh.et.al.,.2008
PCL
10%.w/v
CHL:MeOH
3:1,.v:v
750.±.100.nm.(RF)
Brain-derived.neural.
stem.cells
—
Nisbet.et.al.,.2008
PCL-pp*
16%.w/w
DCM:MeOH.8:2,.v:v
2.26.±.0.08.µm.(RF)
1.03.±.0.03.µm.(AF)
Human.Schwann.cells
—
Chew.et.al.,.2008
CHL:MeOH
3:1,.v:v
100-500.nm.(RF)
Mouse.(129.strain)
embryonic.stem.cells
—
Thouas.et.al.,.2008
20%.w/v
DCM:.DMF.80:20,.v:v
250.nm.(RF/AF)
Mouse.embryonic.stem.
cells.CE3.and.RW4
—
Xie.et.al.,.2009b
PCL-PP
PCL-PP
10-20%.w/v
DCM:DMF
220.±.36.nm
(50.±.3.nm.shell.thickness)
Chick.embryonic.(E8).
dorsal.root.ganglia.
explant
—
Xie.et.al.,.2009a
PCL/GEL
10%.w/v;.1:1,.w:w
TFE
232.±.194.nm.(RF)
160.±.86.nm.(AF)
Rat.Schwann.cell.line
(RT4-D6P2T)
—
Gupta.et.al.,.2009
PCL/CHI
6%.w/w;.70:30,.w:w
HFP
189.±.56.nm.(RF/AF)
Neonatal.mouse.
cerebellum.C17.2.stem.
cells
—
Ghasemi-Mobarakeh.
et.al.,.2008
PCL:CHI,.75:25,.w:w
PCL.in.HFIP,.CHI.in.
TFA/DCM
190.±.26.nm.(RF)
Rat.Schwann.cell.line
RT4-D6P2T
—
Prabhakaran.et.al.,.
2008
*
.
PCL-PP:.PCL.coated.with.polypyrrole
(
continued
)
