Alternative delivery of keratinocytes for epidermal replacement - Biomaterials for Treating Skin Loss - page 120

the dermal epidermal junction come reports of novel systems to facilitate rapid,
simple, cost effective methods of delivery. From the literature it is not possible to
identify any technique as being superior to another in epithelial repair.
Keratinocytes are delivered to the wound as an element within a three-dimen-
sional construct which is beyond the scope of this chapter. The role of a technique
with minimal donor sites and the potential to expand the surface area covered to
1:80 and greater, allows exploration of the indications for use. Rapid cover of
partial thickness injury with dermal preservation reduces the risk of permanent
scarring. The technique also provides the opportunity to resurface scars to improve
the contour and colour using a small site matched donor site.
In reviewing the outcomes it is essential to consider the cost, convenience and
complications as use of the technology progresses.

8.6 References

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4 O'Connor NE, Mulliken JB, Banks-Schlegel S, Kehinde O and Green H, 'Grafting of
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5 Wood FM, Kolybaba ML and Allen P, 'The use of cultured epithelial autograft in the
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