Biomedical Engineering Reference
In-Depth Information
Figure 7.4
Schematic view of antibody-antigen binding.
multiple, noncovalent, interactions, like hydrogen bonds, van der Waals forces or
Coulombic interactions. As for DNA, it is a reversible equilibrium reaction, called
immunoreaction. Biologists use the term affinity to name the interaction force be-
tween antibody and antigen.
7.2.3 Biochip Technology
Biochips derived directly from the principle of biorecognition. First, let us consider
two Eppendorf tubes, each one functionalized with a specific antibody (Figure 7.5).
In such a case, we want to detect a precise antigen that can be recognized by the
grafted antibodies. First, the samples are filled into the Eppendorf tubes, and after
Figure 7.5
Principle of biorecognition (in an Eppendorf tube).
