Biology Reference
In-Depth Information
TABLE I (
Continued
)
Substrate/op-
posite base
Resolution
(
˚
)
PDB ID
(Reference)
Protein
Mutation
Complex
Substrate specificity
1KFV
58
8-oxoG, FapyG, Me-FapyG, FapyA, Hyd
58,60,63,68,69
LlaFpg
P1G
RC
Pr:C
2.55
1TDZ
60
D
P1
LRC
cFapydG:C
1.80
1NNJ
63
P1G
RC
Pr:C
1.90
P1G
RC
THF:C
1.90
1PJJ
-
RC
Pr:C
1.90
1PJI
-
RC
THF:C
1.95
1PM5
1XC8
68
-
RC
cFapydG:C
1.95
-
RC
N7-Benzyl-
FapyG:C
1.90
3C58
2XZF
69
-
LRC
cHyd:C
1.80
-
DPC
cHyd:C
1.80
2XZU
1K3W
56
Tg, 5-OHU, 5-OHC, DHT, DHU, Sp, Gh
34,72,78,79
EcoNei
SBI
-
1.42
SBI
-
1.25
1K3X
1Q39
62
-
-
-
2.80
E2A
-
-
2.30
1Q3C
R252A
-
-
2.05
1Q3B
1TDH
61
NEIL1
D
C-terminal56
-
-
2.10
Sp
¼
Gh
Tg
DHU
5-OHU
5-
>
>
>
>
OHC
DHT
FapyG
¼
FapyA
8-
>
>
oxoG
30,36,39,44,61,80,81
3A46
67
MvNei1
-
RC
THF:C
2.20
Sp
¼
Gh
Tg
5-OHU
5-OHC
DHT
¼
DHU
8-
>
>
>
>
oxoG
39,67,82
-
-
2.60
3A42
-
-
2.30
3A45
2.1
˚
3VK7
104
MvNeil1 E3Q
RC
Tg:C
2.0
˚
3VK8
104
E3Q
RC
5-OHU:G
SBI, Schiff-base intermediate; DXL, disulfide cross-linking; RC, recognition complex; LRC, lesion recognition complex; DPC, DNA-protein covalent; IC, interrogation
complex; CC, control complex; EC, encounter complex; XGC, extrahelical G complex; Hyd or cHyd, where c refers to a carbanucleoside, 5-hydroxy-5-methylhydantoin.
