Biology Reference
In-Depth Information
TABLE I
S
UMMARY OF
C
URRENT
C
RYSTAL
S
TRUCTURES OF THE
F
PG
/N
EI
G
LYCOSYLASES
Substrate/op-
posite base
Resolution
(
˚
)
PDB ID
(Reference)
Protein
Mutation
Complex
Substrate specificity
1EE8
54
8-oxoG, FapyG, Me-FapyG, FapyA
54
TthFpg
-
-
1.90
1K82
55
8-oxoG, FapyG, Me-FapyG, FapyA, Gh
6,18,72-77
EcoFpg
-
SBI
-
2.10
Sp
¼
1L1Z
57
8-oxoG, FapyG, Me-FapyG, FapyA
57,59,64-66
BstFpg
-
SBI
-
1.70
-
SBI
-
2.40
1L2B
-
RC
rAb:C
1.80
1L1T
-
RC
rAb:T
2.20
1L2C
-
RC
rAb:G
2.00
1L2D
1R2Y
59
E3Q
LRC
8-oxoG:C
2.34
1R2Z
64
E3Q
LRC
DHU:C
1.63
E3Q-DXL
CC1
8-oxoG:C
2.35
2F5S
E3Q-DXL
CC2
8-oxoG:C
2.35
2F5Q
E3Q-DXL
IC1
A:T
2.00
2F5N
E3Q-DXL
IC2
A:T
2.00
2F5P
E3Q-DXL
IC3
G:C
2.05
2F5O
3GPY
65
E3Q-DXL
LRC3
8-oxoG:C
1.85
D
220-235-DXL
EC3
8-oxoG:C
1.89
3GO8
V222P-DXL
EC3
8-oxoG:C
2.05
3GP1
T224P-DXL
EC3
8-oxoG:C
2.15
3GPP
D
220-235-DXL
EC4
8-oxoG:C
1.62
3GPU
D
220-235-DXL
IC4
G:C
1.78
3GPX
E3Q-DXL
LRC5
8-oxoG:C
1.70
3GQ4
D
220-235-DXL
EC5
8-oxoG:C
1.83
3GQ3
V222P-DXL
IC5
G:C
1.90
3GQ5
3JR4
66
N174C-DXL
XGC
G:C
2.60
N174C-DXL
LRC
8-oxoG:C
1.70
3JR5
(
Continues
)
