A Simple Method to Detect Allostery in GPCR Dimers - Methods in Cell Biology - page 174

Limbird, L. E. (2004). The receptor concept: A continuing evolution. Molecular Interventions ,
4 , 326-336.
Litschig, S., Gasparini, F., Rueegg, D., Stoehr, N., Flor, P. J., Vranesic, I., et al. (1999). CPCCOEt,
a noncompetitive metabotropic glutamate receptor 1 antagonist, inhibits receptor signaling
without affecting glutamate binding. Molecular Pharmacology , 55 , 453-461.
Maillet, E. L., Pellegrini, N., Valant, C., Bucher, B., Hibert, M., Bourguignon, J. J., et al.
(2007). A novel, conformation-specific allosteric inhibitor of the tachykinin NK2 receptor
(NK2R) with functionally selective properties. The FASEB Journal , 21 , 2124-2134.
May, L. T., Leach, K., Sexton, P. M., & Christopoulos, A. (2007). Allosteric modulation of
G protein-coupled receptors. Annual Review of Pharmacology and Toxicology , 47 , 1-51.
Milligan, G. (2009). G protein-coupled receptor hetero-dimerization: Contribution to pharma-
cology and function. British Journal of Pharmacology , 158 , 5-14.
Palanche, T., Ilien, B., Zoffmann, S., Reck, M. P., Bucher, B., Edelstein, S. J., et al. (2001). The
neurokinin A receptor activates calcium and cAMP responses through distinct conforma-
tional states. The Journal of Biological Chemistry , 276 , 34853-34861.
Peeters, M. C., van Westen, G. J., Guo, D., Wisse, L. E., Muller, C. E., Beukers, M. W., et al.
(2011). GPCR structure and activation: An essential role for the first extracellular loop in
activating the adenosine A2B receptor. The FASEB Journal , 25 , 632-643.
Peri, K. G., Quiniou, C., Hou, X., Abran, D., Varma, D. R., Lubell, W. D., et al. (2002).
THG113: A novel selective FP antagonist that delays preterm labor. Seminars in Perina-
tology , 26 , 389-397.
P ´ trin, D., & H ´ bert, T. E. (2011). Imaging-based approaches to understanding G protein-
coupled receptor signalling complexes. Methods in Molecular Biology , 756 , 37-60.
Prinster, S. C., Hague, C., & Hall, R. A. (2005). Heterodimerization of g protein-coupled re-
ceptors: Specificity and functional significance. Pharmacological Reviews , 57 , 289-298.
Proska, J., & Tucek, S. (1994). Mechanisms of steric and cooperative actions of alcuronium on
cardiac muscarinic acetylcholine receptors. Molecular Pharmacology , 45 , 709-717.
Rashid, A. J., So, C. H., Kong, M. M., Furtak, T., El-Ghundi, M., Cheng, R., et al. (2007). D1-
D2 dopamine receptor heterooligomers with unique pharmacology are coupled to rapid
activation of Gq/11 in the striatum. Proceedings of the National Academy of Sciences
of the United States of America , 104 , 654-659.
Terrillon, S., & Bouvier, M. (2004). Roles of G-protein-coupled receptor dimerization. EMBO
Reports , 5 , 30-34.
Urizar, E., Montanelli, L., Loy, T., Bonomi, M., Swillens, S., Gales, C., et al. (2005). Glyco-
protein hormone receptors: Link between receptor homodimerization and negative coop-
erativity. The EMBO Journal , 24 , 1954-1964.
Urwyler, S. (2011). Allosteric modulation of family C G-protein-coupled receptors: Frommo-
lecular insights to therapeutic perspectives. Pharmacological Reviews , 63 , 59-126.
Valant, C., Maillet, E., Bourguignon, J. J., Bucher, B., Utard, V., Galzi, J. L., et al. (2009).
Allosteric functional switch of neurokinin A-mediated signaling at the neurokinin NK2
receptor: Structural exploration. Journal of Medicinal Chemistry , 52 , 5999-6011.
Valant, C., Sexton, P. M., & Christopoulos, A. (2009). Orthosteric/allosteric bitopic ligands:
Going hybrid at GPCRs. Molecular Interventions , 9 , 125-135.
Varney, M. A., Cosford, N. D., Jachec, C., Rao, S. P., Sacaan, A., Lin, F. F., et al. (1999).
SIB-1757 and SIB-1893: Selective, noncompetitive antagonists of metabotropic glutamate
receptor type 5. The Journal of Pharmacology and Experimental Therapeutics , 290 ,
170-181.