Chemistry Reference
In-Depth Information
Polyvinylpyrrolidone
Structure
n
>
1,000,000
N
O
CH
CH
2
n
Synonyms
PVP, povidone, polyvidone, 1-vinyl-2-
pyrrolidinone, Kollidon, Polyplasdone, Povipharm
Molecular weight range
(g/mol)
2500
-
3,000,000
Solubility parameter,
δ
27.7
(MPa
0.5
)
T
g
range (
C)
120
-
174
°
Water uptake (% water at
75% RH)
30-40%
Solvent solubility
Freely soluble in chloroform, 95% ethanol,
ketones, methanol, and water
pH range where soluble
1-10
Amenable methods of
dispersion manufacture
Melt extrusion, spray drying
Cesamet
, Rezulin
1
Use in marketed products
Grade (K-value)
∼
MW
T
g
(
°
C)
12
2,500
120
15
8000
-
17
10,000
126
25
30,000
160
29/32
5000
164
60
400,000
-
90
1,000,000
174
120
3,000,000
-
