Biology Reference
In-Depth Information
the repair of damaged blood vessels or develop new vessels as needed. This chapter
reviews the current lineage relationships among all the cells called EPC and will
clear the terminology used in EPC research. Furthermore, an overview of the clinical
and in vitro research, as well as cytokine and drug interactions and potential EPC appli-
cations, is given.
ABBREVIATIONS
acLDL
acetylated low-density lipoprotein
AMI
acute myocardial infarction
BM
bone marrow
CABG
coronary artery bypass graft
CAC
circulating angiogenic cell
CAD
coronary artery disease
CB
cord blood
CD34
cluster of differentiation 34
CECs
circulating endothelial cells
COPD
chronic obstructive pulmonary disease
CPC
circulating progenitor cell
CXCR4
Cys-X-Cys chemokine receptor 4
ECFCs
endothelial colony-forming cells, also termed outgrowth epithelial cells (OEC)
eNOS
endothelial nitric oxide synthase
EPCs
endothelial progenitor cells
HIF-1a
hypoxia-inducible factor-1a
HSCs
hematopoietic stem cells
HUVEC
human umbilical cord vein endothelial cell
IL
interleukin
KDR
kinase insert domain receptor
LDL
low-density lipoprotein
MC
myeloid cells
MI
myocardial infarction
MNC
mononuclear cell
MSC
mesenchymal stem cell
OSA
obstructive sleep apnea
PB
peripheral blood
RA
rheumatoid arthritis
SA
sprouting angiogenesis
SDF-1a
stromal-derived factor-1a
SSc
systemic sclerosis
TNF-
a
tumor necrosis factor-
a
UEA Ulex europaeus
agglutinin
VEGF
vascular endothelial growth factor
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