Biomedical Engineering Reference
In-Depth Information
SCHEME 3.9
Diastereoselective Diels-Alder cycloaddition reaction of a diene generated
through enyne ring-closing metathesis reactions.
3.2.2
Inverse Electron-Demand Diels-Alder Reaction
Lindsley et al. reported the synthesis of carpanone-like molecules using an endo-
selective inverse electron-demand Diels-Alder cycloaddition reaction (Scheme 3.11)
[24]. The Diels-Alder precursor was synthesized through diastereoselective oxidative
SCHEME 3.10
Oligomer-based build/couple/pair pathway. Diels-Alder reaction of dienes
synthesized by Ru-catalyzed metathesis reactions.
